User profiles for Enkhzol Malchinkhuu

Enkhzol Malchinkhuu MD, PhD

Associate professor, Department of Pediatrics, Mongolian National University of Medical …
Verified email at mnums.edu.mn
Cited by 3062

Tumor-Evoked Regulatory B Cells Promote Breast Cancer Metastasis by Converting Resting CD4+ T Cells to T-Regulatory Cells

…, RE Gress, R Sen, K Wejksza, E Malchinkhuu… - Cancer research, 2011 - AACR
Pulmonary metastasis of breast cancer requires recruitment and expansion of T-regulatory
cells (Treg) that promote escape from host protective immune cells. However, it remains …

Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors

…, K Sato, N Murata, A Damirin, E Malchinkhuu… - Molecular …, 2003 - ASPET
Lysophosphatidic acid (LPA) exerts a variety of biological responses through specific receptors:
three subtypes of the EDG-family receptors, LPA 1 , LPA 2 , and LPA 3 (formerly known …

High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors

T Kimura, K Sato, E Malchinkhuu… - … , and vascular biology, 2003 - Am Heart Assoc
Objective— Plasma high-density lipoprotein (HDL) level is inversely correlated with the risk
of atherosclerosis. However, the cellular mechanism by which HDL exerts antiatherogenic …

[HTML][HTML] TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor

…, A Damirin, K Sato, M Komachi, E Malchinkhuu… - Journal of Biological …, 2004 - ASBMB
T cell death-associated gene 8 (TDAG8) has been reported to be a receptor for psychosine.
Ovarian cancer G-protein-coupled receptor 1 (OGR1) and GPR4, G-protein-coupled …

Critical role of ABCA1 transporter in sphingosine 1‐phosphate release from astrocytes

K Sato, E Malchinkhuu, Y Horiuchi… - Journal of …, 2007 - Wiley Online Library
Sphingosine 1‐phosphate (S1P) is accumulated in lipoproteins, especially high‐density
lipoprotein (HDL), in plasma. However, it remains uncharacterized how extracellular S1P is …

[HTML][HTML] Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1

T Yamada, K Sato, M Komachi, E Malchinkhuu… - Journal of biological …, 2004 - ASBMB
Cytokines and growth factors in malignant ascites are thought to modulate a variety of cellular
activities of cancer cells and normal host cells. The motility of cancer cells is an especially …

Thymic stromal lymphopoietin is a key mediator of breast cancer progression

…, Y Rochman, M Bodogai, E Malchinkhuu… - The Journal of …, 2011 - journals.aai.org
Inflammation is a double-edged sword that can promote or suppress cancer progression. In
this study, we report that thymic stromal lymphopoietin (TSLP), an IL-7–like type 1 …

LPA 1 receptors mediate stimulation, whereas LPA 2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to …

M Komachi, H Tomura, E Malchinkhuu, M Tobo… - …, 2009 - academic.oup.com
Malignant ascites from pancreatic cancer patients has been reported to stimulate migration
of pancreatic cancer cells through lysophosphatidic acid (LPA) and LPA 1 receptors. Indeed, …

[HTML][HTML] Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells

E Malchinkhuu, K Sato, Y Horiuchi, C Mogi, S Ohwada… - Oncogene, 2005 - nature.com
A potential role for 1-oleoyl-sn-glycero-3-phosphate or lysophosphatidic acid (LPA) and
sphingosine-1-phosphate (S1P) in the regulation of malignant diseases has been widely …

S1P2 receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN

E Malchinkhuu, K Sato, T Maehama, C Mogi… - Biochemical and …, 2008 - Elsevier
Sphingosine 1-phosphate (S1P) induced the inhibition of glioma cell migration. Here, we
characterized the signaling mechanisms involved in the inhibitory action by S1P. In human GNS…