User profiles for Eric Masson

Eric Masson

Professor and Roenigk Chair of Chemistry, Department of Chemistry and Biochemistry, Ohio …
Verified email at ohio.edu
Cited by 2504

Cucurbituril chemistry: a tale of supramolecular success

E Masson, X Ling, R Joseph, L Kyeremeh-Mensah… - Rsc Advances, 2012 - pubs.rsc.org
This review highlights the past six year advances in the blossoming field of cucurbit[n]uril
chemistry. Because of their exceptional recognition properties in aqueous medium, these …

Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.

E Masson, MV Relling, TW Synold… - The Journal of …, 1996 - Am Soc Clin Investig
Methotrexate (MTX) is one of the most widely used drugs for the treatment of childhood
acute lymphoblastic leukemia (ALL) and is commonly given in high doses. However, the …

A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic …

…, G Garcia-Manero, J Beck, F Ravandi, E Masson… - Clinical Cancer …, 2006 - AACR
Purpose: LBH589 is a novel histone deacetylase inhibitor that inhibits proliferation and induces
apoptosis in tumor cell lines. In this phase I study, LBH589 was administered iv as a 30-…

[PDF][PDF] Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced …

…, A Higginson, A Kay, L Lee, E Masson… - Journal of Clinical …, 2005 - researchgate.net
Purpose PTK787/ZK 222584 (PTK/ZK) is an oral angiogenesis inhibitor targeting all known
vascular endothelial growth factor (VEGF) receptor tyrosine kinases, including VEGFR-1/Flt-1…

Torsional barriers of substituted biphenyls calculated using density functional theory: a benchmarking study

E Masson - Organic & biomolecular chemistry, 2013 - pubs.rsc.org
The barriers of torsional isomerization of 13 substituted biphenyls, ranging from 7.4 to 44
kcal mol−1, were calculated using 9 density functionals (the BP86 and B97D GGAs, the meta-…

Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours

…, J Hennig, B Morgan, D Lebwohl, E Masson… - European Journal of …, 2005 - Elsevier
The family of VEGF receptors are important mediators of angiogenesis, which is essential for
tumour growth and metastasis. PTK/ZK is a multiple VEGF receptor inhibitor that blocks the …

Exposure–response relationships of the efficacy and safety of ipilimumab in patients with advanced melanoma

Y Feng, A Roy, E Masson, TT Chen, R Humphrey… - Clinical Cancer …, 2013 - AACR
Purpose: This retrospective analysis was conducted to characterize ipilimumab exposure–response
relationships for measures of efficacy and safety in patients with advanced …

Stabilization of cucurbituril/guest assemblies via long-range coulombic and CH··· O interactions

…, A Nkrumah, RJ Clark, E Masson - Journal of the American …, 2014 - ACS Publications
Cucurbit[n]urils (CB[n], n = 6–8) interact strongly with metal-bound 4′-substituted terpyridine
ligands (M = Fe(II) and Ir(III)) via CH···O hydrogen bonding, despite significant separation …

Randomized phase I pharmacokinetic study of ipilimumab with or without one of two different chemotherapy regimens in patients with untreated advanced melanoma

J Weber, O Hamid, A Amin, S O'Day, E Masson… - Cancer immunity, 2013 - AACR
We describe a randomized three-arm phase I study of ipilimumab administered alone (I
group) or in combination with dacarbazine (D group) or carboplatin/paclitaxel (CP group) in …

Digital breast tomosynthesis using an amorphous selenium flat panel detector

M Bissonnette, M Hansroul, E Masson… - … 2005: Physics of …, 2005 - spiedigitallibrary.org
A prototype breast tomosynthesis system has been developed, allowing a total angular view
of ±25. The detector used in this system is an amorphous selenium direct-conversion digital …