The steroid hormone estrogen regulates many functionally unrelated processes in numerous
tissues. Although it is traditionally thought to control transcriptional activation through the …

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …

Estrogen is a hormone critical in the development, normal physiology and pathophysiology
1 of numerous human tissues 2 . The effects of estrogen have traditionally been solely …

Estrogens mediate profound effects throughout the body and regulate physiological and
pathological processes in both women and men. The low prevalence of many diseases in …

Steroids play an important role in the regulation of normal physiology and the treatment of
disease. Steroid receptors have classically been described as ligand-activated transcription …

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …

Estrogen is central to many physiological processes throughout the human body. We have
previously shown that the G protein–coupled receptor GPR30 (also known as GPER), in …

The G protein-coupled receptor 30 (GPR 30) has been identified as the non-genomic estrogen
receptor, and G-1, the specific ligand for GPR30. With the use of a polyclonal antiserum …

Estrogens play a crucial role in the development of ovarian tumors; however, the signal
transduction pathways involved in hormone action are still poorly defined. The orphan G protein–…

The effects of estrogen are widespread throughout the body. Although the classical nuclear
estrogen receptors have been known for many years to decades and their primary modes of …