The striatum, which is the major component of the basal ganglia in the brain, is regulated in
part by dopaminergic input from the substantia nigra. Severe movement disorders result from …

A heptadecapeptide was identified and purified from porcine brain tissue as a ligand for an
orphan heterotrimeric GTP- binding protein (G protein)- coupled receptor (LC132) that is …

… David Sibley and Frederick Monsma review the molecular characteristics of the recently
cloned dopamine receptors and discuss prospects for the cloning … Monsma, jr is …

The authors examined the affinities of 36 typical and atypical antipsychotic agents for the
cloned rat 5-hydroxytryptamine-6 (5-HT6) and rat 5-hydroxytryptamine-7 (5-HT7) receptors in …

GPR54 is a G-protein-coupled receptor that displays a high percentage of identity in the
transmembrane domains with the galanin receptors. The ligand for GPR54 has been identified …

We have used the polymerase chain reaction technique to selectively amplify a guanine
nucleotide-binding protein-coupled receptor cDNA sequence from rat striatal mRNA that …

DOPAMINE receptors belong to a large class of neurotransmitter and hormone receptors
that are linked to their signal transduction pathways through guanine nucleotide binding …

We have utilized the polymerase chain reaction technique to selectively amplify a G protein-coupled
receptor cDNA from rat kidney proximal convoluted tubule mRNA, which exhibits …

In order to clone the D1 dopamine receptor linked to adenylyl cyclase activation, the polymerase
chain reaction was used with highly degenerate primers to selectively amplify a cDNA …

ADP plays a critical role in modulating thrombosis and hemostasis. ADP initiates platelet
aggregation by simultaneous activation of two G protein–coupled receptors, P2Y1 and P2Y12. …