User profiles for F. Leoni
 | Fabio LeoniVerified email at ffn.ub.es Cited by 286 |
[HTML][HTML] Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia
…, T De Witte, B Labar, L Resegotti, F Leoni… - … England Journal of …, 1995 - Mass Medical Soc
Background Allogeneic or autologous bone marrow transplantation and intensive
consolidation chemotherapy are used to treat acute myelogenous leukemia in a first complete …
consolidation chemotherapy are used to treat acute myelogenous leukemia in a first complete …
Clinically useful prognostic factors in acute myeloid leukemia
F Ferrara, S Palmieri, F Leoni - Critical reviews in oncology/hematology, 2008 - Elsevier
The clinical outcome of acute myeloid leukemia (AML) is extremely variable, ranging from
survival of a few days to cure. Different clinical and biological features at diagnosis have been …
survival of a few days to cure. Different clinical and biological features at diagnosis have been …
[HTML][HTML] Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis
LAB Joosten, F Leoni, S Meghji, P Mascagni - Molecular medicine, 2011 - Springer
Inhibition of histone deacetylases (HDAC) has been shown to modulate gene expression
and cytokine production after stimulation with several stimuli. In the present study, the …
and cytokine production after stimulation with several stimuli. In the present study, the …
The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines
F Leoni, A Zaliani, G Bertolini, G Porro… - Proceedings of the …, 2002 - National Acad Sciences
Suberoylanilide hydroxamic acid (SAHA) is a hydroxamic acid-containing hybrid polar
molecule; SAHA specifically binds to and inhibits the activity of histone deacetylase. Although …
molecule; SAHA specifically binds to and inhibits the activity of histone deacetylase. Although …
Genetic analysis of Cryptosporidium from 2414 humans with diarrhoea in England between 1985 and 2000
F Leoni, C Amar, G Nichols… - Journal of medical …, 2006 - microbiologyresearch.org
The characterization of Cryptosporidium using DNA extracted from whole faecal samples
collected from 2414 humans with diarrhoea in England between 1985 and 2000 where …
collected from 2414 humans with diarrhoea in England between 1985 and 2000 where …
The physics of empty liquids: From patchy particles to water
… Putting together the equations above we arrive at an expression for the free energy per
particle f = F/N in terms of the bonding … The Helmholtz free energy per particle f = F/N is …
particle f = F/N in terms of the bonding … The Helmholtz free energy per particle f = F/N is …
[HTML][HTML] The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo
F Leoni, G Fossati, EC Lewis, JK Lee, G Porro… - Molecular …, 2005 - Springer
We studied inhibition of histone deacetylases (HDACs), which results in the unraveling of
chromatin, facilitating increased gene expression. ITF2357, an orally active, synthetic inhibitor …
chromatin, facilitating increased gene expression. ITF2357, an orally active, synthetic inhibitor …
Histone hyperacetylation is associated with amelioration of experimental colitis in mice
…, A Batra, I Fedke, M Zeitz, HA Lehr, F Leoni… - The Journal of …, 2006 - journals.aai.org
Inhibitors of histone deacetylases (HDAC) are being studied for their antiproliferative effects
in preclinical cancer trials. Recent studies suggest an anti-inflammatory role for this class of …
in preclinical cancer trials. Recent studies suggest an anti-inflammatory role for this class of …
Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse …
…, P Mascagni, G Fossati, F Leoni, F Moroni… - Molecular …, 2006 - ASPET
Pharmacological manipulation of gene expression is considered a promising avenue to
reduce postischemic brain damage. Histone deacetylases (HDACs) play a central role in …
reduce postischemic brain damage. Histone deacetylases (HDACs) play a central role in …
Characteristics of May 5–6, 1998 volcaniclastic debris flows in the Sarno area (Campania, southern Italy): relationships to structural damage and hazard zonation
G Zanchetta, R Sulpizio, MT Pareschi, FM Leoni… - Journal of volcanology …, 2004 - Elsevier
The destructive power of debris flows on alluvial fan surfaces was investigated by studying
the event of May 5–6, 1998 in the Sarno area (Campania, southern Italy). We assessed some …
the event of May 5–6, 1998 in the Sarno area (Campania, southern Italy). We assessed some …