Driving with no brakes: molecular pathophysiology of Kv7 potassium channels
Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here,
we describe their molecular architecture, physiological roles, and involvement in …
we describe their molecular architecture, physiological roles, and involvement in …
Molecular pharmacology and therapeutic potential of neuronal Kv7-modulating drugs
F Miceli, MV Soldovieri, M Martire… - Current opinion in …, 2008 - Elsevier
The Kv7 potassium channel family encompasses five members (from Kv7.1 to Kv7.5) having
distinct expression pattern and functional role. Although Kv7.1 is prevalently expressed in …
distinct expression pattern and functional role. Although Kv7.1 is prevalently expressed in …
[HTML][HTML] Cytokine storm in aged people with CoV-2: possible role of vitamins as therapy or preventive strategy
…, M Battilana, PE Orlandi, F Del Forno, F Miceli… - Aging clinical and …, 2020 - Springer
Background In December 2019, a novel human-infecting coronavirus, SARS-CoV-2, had
emerged. The WHO has classified the epidemic as a “public health emergency of international …
emerged. The WHO has classified the epidemic as a “public health emergency of international …
Genotype–phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits
Mutations in the K V 7.2 gene encoding for voltage-dependent K + channel subunits cause
neonatal epilepsies with wide phenotypic heterogeneity. Two mutations affecting the same …
neonatal epilepsies with wide phenotypic heterogeneity. Two mutations affecting the same …
Stromal-epithelial interactions modulate estrogen responsiveness in normal human endometrium
E Pierro, F Minici, O Alesiani, F Miceli… - Biology of …, 2001 - academic.oup.com
The coculture of endometrial epithelial cells (EEC) with stromal cells (ESC) allows achievement
of an improved in vitro system for studying interactions between cells via soluble signals. …
of an improved in vitro system for studying interactions between cells via soluble signals. …
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7. 2 and Kv7. 3 potassium channel subunits
… following equation: τ = (τ f A f + τ s A s )/(A f + A s ), where A f and A s indicate the amplitude
of the fast and slow exponential components, respectively, and τ f and τ s indicate the time …
of the fast and slow exponential components, respectively, and τ f and τ s indicate the time …
Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels
… Fluorescence changes were calculated with the following ratio: (F t − F 0 /F 0 ) where F 0
is the basal fluorescence before the addition of NaHS or K v 7-activators, and F t is the …
is the basal fluorescence before the addition of NaHS or K v 7-activators, and F t is the …
Non‐destructive Determination of Leaf Chlorophyll Content in Four Crop Species1
F Castelli, R Contillo, F Miceli - Journal of Agronomy and Crop …, 1996 - Wiley Online Library
A recent non‐destructive technique allows estimation of leaf chlorophyll content using the
portable SPAD‐502 chlorophyll meter. Measurements were taken on four species (winter …
portable SPAD‐502 chlorophyll meter. Measurements were taken on four species (winter …
Decompensation in advanced nonalcoholic fatty liver disease may occur at lower hepatic venous pressure gradient levels than in patients with viral disease
…, J Chang, H Masnou, A Zipprich, F Miceli… - Clinical …, 2022 - Elsevier
Background & Aims Portal hypertension is the strongest predictor of hepatic decompensation
and death in patients with cirrhosis. However, its discriminatory accuracy in patients with …
and death in patients with cirrhosis. However, its discriminatory accuracy in patients with …
Novel KCNQ2 and KCNQ3 Mutations in a Large Cohort of Families with Benign Neonatal Epilepsy: First Evidence for an Altered Channel Regulation by Syntaxin‐1A
…, B Heron, E Bourel, P Ambrosino, F Miceli… - Human …, 2014 - Wiley Online Library
Mutations in the KCNQ 2 and KCNQ 3 genes encoding for K v 7.2 ( KCNQ 2; Q 2) and K v
7.3 ( KCNQ 3; Q 3) voltage‐dependent K + channel subunits, respectively, cause neonatal …
7.3 ( KCNQ 3; Q 3) voltage‐dependent K + channel subunits, respectively, cause neonatal …