[HTML][HTML] Revised role for Hfq bacterial regulator on DNA topology

…, F Geinguenaud, P Recouvreux, T Bizien, F Busi… - Scientific Reports, 2018 - nature.com
Hfq is a pleiotropic regulator that mediates several aspects of bacterial RNA metabolism. The
protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, …

CYP3A5 mRNA degradation by nonsense-mediated mRNA decay

F Busi, T Cresteil - Molecular pharmacology, 2005 - ASPET
The total CYP3A5 mRNA level is significantly greater in carriers of the CYP3A5 * 1 allele
than in CYP3A5 * 3 homozygotes. Most of the CYP3A5 * 3 mRNA includes an intronic …

Biotransformation of Trichoderma spp. and their tolerance to aromatic amines, a major class of pollutants

…, LC Bui, P Silar, L Chan Ho Tong, F Busi… - Applied and …, 2013 - Am Soc Microbiol
Trichoderma spp. are cosmopolitan soil fungi that are highly resistant to many toxic compounds.
Here, we show that Trichoderma virens and T. reesei are tolerant to aromatic amines (AA…

Dexamethasone as a probe for docetaxel clearance

F Puisset, E Chatelut, F Dalenc, F Busi… - Cancer chemotherapy …, 2004 - Springer
Purpose A pilot study was conducted in 23 patients in order to assess the correlation between
docetaxel clearance (CL) and pharmacokinetics of dexamethasone. Dexamethasone is …

Carbon Black Nanoparticles Impair Acetylation of Aromatic Amine Carcinogens through Inactivation of Arylamine N-Acetyltransferase Enzymes

E Sanfins, J Dairou, S Hussain, F Busi, AF Chaffotte… - ACS …, 2011 - ACS Publications
Carbon black nanoparticles (CB NPs) and their respirable aggregates/agglomerates are
classified as possibly carcinogenic to humans. In certain industrial work settings, CB NPs …

[HTML][HTML] Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling

…, X Xu, I Haddad, J Vinh, JM Dupret, F Busi… - Journal of Biological …, 2019 - ASBMB
Protein tyrosine phosphatase, nonreceptor type 2 (PTPN2) is mainly expressed in hematopoietic
cells, where it negatively regulates growth factor and cytokine signaling. PTPN2 is an …

Human arylamine N-acetyltransferase 1 is inhibited by the dithiocarbamate pesticide thiram

…, C Mathieu, J Berthelet, R Duval, LC Bui, F Busi… - Molecular …, 2017 - ASPET
Thiram (tetramethylthiuram disulfide) is a representative dithiocarbamate (DTC) pesticide
used in both the field and as a seed protectant. The widespread use of Thiram and other DTC …

Human arylamine N-acetyltransferase 1: a drug-metabolizing enzyme and a drug target?

F Rodrigues-Lima, J Dairou, F Busi… - Current drug …, 2010 - ingentaconnect.com
Human arylamine N-acetyltransferase 1 (NAT1) is a phase II xenobiotic-metabolizing enzyme
(XME) involved in the biotransformation of many aromatic and heterocyclic amines. This …

Riboregulation of the bacterial actin-homolog MreB by DsrA small noncoding RNA

…, S Trépout, S Marco, A Taghbalout, F Busi… - Integrative …, 2015 - academic.oup.com
The bacterial actin-homolog MreB is a key player in bacterial cell-wall biosynthesis and is
required for the maintenance of the rod-like morphology of Escherichia coli. However, how …

[BOOK][B] Pesticide-derived aromatic amines and their biotransformation

…, A Cocaign, C Mougin, F Rodrigues-Lima, F Busi… - 2011 - researchgate.net
Aromatic amines (AA) are an important and diversified class of pollutants, including industrial
products, drugs, combustion products, pesticides or dyes. Some AA, in particular pesticide-…