Increased glutathione S-transferase activity and glutathione content in an insecticide-resistant strain of Tribolium castaneum (Herbst)

GF Reidy, HA Rose, S Visetson, M Murray - Pesticide Biochemistry and …, 1990 - Elsevier
Cyfluthrin resistance in Tribolium castaneum (Herbst) was associated with increases in both
glutathione (GSH) concentration and glutathione S-transferase (GST) activity. Cytosolic …
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Inhibition of oxidative drug metabolism by orphenadrine: in vitro and in vivo evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics.

GF Reidy, I Mehta, M Murray - Molecular Pharmacology, 1989 - ASPET
The anti-parkinsonian agent orphenadrine has been shown to form an in vitro metabolic
intermediate (MI) complex in hepatic microsomes isolated from phenobarbital (PB)-treated rats. …
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The effects of propiconazole on hepatic xenobiotic biotransformation in the rat

C Leslie, GF Reidy, NH Stacey - Biochemical pharmacology, 1988 - Elsevier
Propiconazole, a foliar fungicide used for agricultural purposes was studied for its effects on
the hepatic xenobiotic biotransformation in the rat. Rats were given an intraperitoneal …
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[CITATION][C] Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents.

M Murray, GF Reidy - Pharmacological Reviews, 1990 - europepmc.org
… Reidy GF …
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In vitro formation of an inhibitory complex between an isosafrole metabolite and rat hepatic cytochrome P-450 PB-B.

M Murray, GF Reidy - Drug metabolism and disposition, 1989 - ASPET
A series of in vitro studies was performed, in rat liver microsomes, in which metabolite
intermediate (MI) complexation of cytochrome P-450 (P-450) by the methylenedioxyphenyl …
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Effect of length of exposure to malathion on xenobiotic biotransformation in male rat liver

GF Reidy, HA Rose, NH Stacey - Toxicology letters, 1987 - Elsevier
The effect of exposure to malathion on several parameters of hepatic xenobiotic biotransformation
was studied in male Sprague-Dawley rats. Groups of rats dosed ip daily for 1 or 2 …
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Induction of xenobiotic biotransformation by the insecticide chlordimeform, a metabolite 4-chloro-o-toluidine and a structurally related chemical o-toluidine

C Leslie, GF Reidy, M Murray, NH Stacey - Biochemical pharmacology, 1988 - Elsevier
Chlordimeform, 4-chloro-o-toluidine and o-toluidine have all been found to have carcinogenic
properties. Due to an empirical link between such properties and alteration of some …
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Evidence for complexation of P-450 IIC6 by an orphenadrine metabolite

GF Reidy, M Murray - Biochemical and biophysical research …, 1990 - Elsevier
Removal of the orphenadrine metabolite from its complex with rat liver P-450 IIB1 is associated
with a discrepancy in the reactivation of IIB1 activity. Two possible explanations are that …
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Effects of picloram on xenobiotic biotransformation in rat liver

GF Reidy, HA Rose, NH Stacey - Xenobiotica, 1987 - Taylor & Francis
1. The effect of picloram on model xenobiotic substrate biotransformation in vivo was
studied in female and male rat liver. 2. Treatment with picloram had little effect on epoxide …
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Evidence for cytochrome P-450 multiplicity in the midgut of the cluster caterpillar, Spodoptera litura (F.)

GF Reidy, HA Rose, NH Stacey - Pesticide Biochemistry and Physiology, 1987 - Elsevier
… REIDY. ROSE, AND STACEY … REIDY, ROSE, AND STACEY … GF Reidy. HA Rose,
and NH Stacey, Effects of picloram on xenobiotic biotransformation in rat liver. Xenohioticu. …
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