To identify the transductional mechanisms responsible for the neuroprotective effect of nitric
oxide (NO) during ischemic preconditioning (IPC), we investigated the effects of this …

In the last two decades, there has been a growing interest in unraveling the role that the Na
+ /Ca 2+ exchanger (NCX) plays in the function and regulation of several cellular activities. …

Reactive oxygen species (ROS) have been implicated in the pathophysiology of many
neurologic disorders and brain dysfunction. In the same pathological settings evidence has been …

Over the last few years, although extensive studies have focused on the relevant function
played by the sodium–calcium exchanger (NCX) during focal ischemia, a thorough …

Basal and cold-stimulated TSH plasma levels were measured in rats adapted to warmth after
chronic depletion of brain norepinephrine (NE) by 6-hydroxydopamine (6-OHDA). Injection …

The aim of the present study was to investigate whether K V 3.4 channel subunits are involved
in neuronal death induced by neurotoxic β-amyloid peptides (Aβ). In particular, to test this …

Long-term potentiation (LTP) depends on the coordinated regulation of an ensemble of proteins
related to Ca 2+ homeostasis, including Ca 2+ transporters. One of the major players in …

Hypoxia inducible factor (HIF‐1)‐1α is a specific, oxygen‐sensitive protein that regulates
the activity of HIF‐1, a transcriptional factor that increases after cerebral ischemia and may …

Ischemic preconditioning (IPC), an important endogenous adaptive mechanism of the CNS,
renders the brain more tolerant to lethal cerebral ischemia. The molecular mechanisms …

TNF-related apoptosis inducing ligand (TRAIL), a member of the TNF superfamily released
by microglia, appears to be involved in the induction of apoptosis following focal brain …