The ability to resist the urge to eat requires the proper functioning of neuronal circuits involved
in top-down control to oppose the conditioned responses that predict reward from eating …

Imaging studies have revealed neurochemical and functional changes in the brains of drug-addicted
subjects that provide new insights into the mechanisms underlying addiction. …

The involvement of dopamine in drug reinforcement is well recognized but its role in drug
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs of …

… Gene-Jack Wang was the main clinical coordinator, did the PET scanning, and wrote the
paper. Nora Volkow designed the study, analysed PET scan data, and wrote the paper. Jean …

Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease”
provides recommendations to guide clinicians in the diagnosis, genetic evaluation and family …

The distribution volume ratio (DVR), which is a linear function of receptor availability, is widely
used as a model parameter in imaging studies. The DVR corresponds to the ratio of the …

The ability of drugs of abuse to increase dopamine in nucleus accumbens underlies their
reinforcing effects. However, preclinical studies have shown that with repeated drug exposure …

… Volkow ND, Ding YS, Fowler JS, Wang GJ: Cocaine addiction: hypothesis derived from
imaging studies with PET. J Addict Dis 1996; 15:55-71Crossref, Medline, Google Scholar …

Cocaine blocks the reuptake of dopamine, a neurotransmitter involved in the control of
movement, cognition, motivation and reward. This leads to an increase in extracellular dopamine; …

… Innis RB, Seibyl JP, Scanley BE, Laruelle M, Abi-Dargham A, Wallace E, Baldwin RM,
Zea-Ponce Y, Zoghbi S, Wang S: Single photon emission computed tomographic imaging …