[HTML][HTML] Non-antibiotic drug repositioning as an alternative antimicrobial approach

…, A Rosato, F Corbo, ML Clodoveo, G Fracchiolla… - Antibiotics, 2022 - mdpi.com
The worldwide scenario of antibiotic resistance and the falling number of funds for the
development of novel antibiotics have led research efforts toward the study of specific cost-…

[HTML][HTML] Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complex with …

…, A Galmozzi, S Scurati, F Loiodice, G Fracchiolla… - Journal of Biological …, 2007 - ASBMB
… Cells were sonicated, and the soluble fraction was isolated by centrifugation (35,000 × g
for 45 min). The supernatant was loaded onto an Ni 2+ -nitrilotriacetic acid column (GE …

Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the …

…, F Gilardi, F Loiodice, G Fracchiolla… - Journal of medicinal …, 2008 - ACS Publications
… with phosphate-buffered saline and refed with serum-free medium (Dulbecco’s modified
Eagle medium/F-12 nutrient 1:1, Invitrogen, Milano, Italy) containing 100 U of penicillin G/mL …

[HTML][HTML] Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials

…, F Corbo, GG Carbonara, A Carrieri, G Fracchiolla - PloS one, 2018 - journals.plos.org
Mentha piperita L. essential oil (EO) is employed for external use as antipruritic, astringent,
rubefacient and antiseptic. Several studies demonstrated its significant antiviral, antifungal …

[HTML][HTML] Metabolic Syndrome: A Narrative Review from the Oxidative Stress to the Management of Related Diseases

G Martemucci, G Fracchiolla, M Muraglia, R Tardugno… - Antioxidants, 2023 - mdpi.com
… of 100 g/day for the intake of total sugars containing fructose; taking into account the promotion
of fruit and vegetables, fruit provides about 40 g of sugars, and vegetables 6 g of sugars. …

Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus

C Catella, M Camero, MS Lucente, G Fracchiolla… - Research in veterinary …, 2021 - Elsevier
Feline infectious peritonitis (FIP) is a fatal systemic disease of felids caused by a Coronavirus
(CoV) (FIPV). In spite of its clinical relevance and impact on feline health, currently the …

[HTML][HTML] Antimicrobial Activity of Essential Oils Evaluated In Vitro against Escherichia coli and Staphylococcus aureus

…, S Sblano, M Camero, G Lanave, G Fracchiolla… - Antibiotics, 2022 - mdpi.com
The spread of extended-spectrum β-lactamase-producing Escherichia coli and methicillin-resistant
Staphylococcus aureus has caused a reduction in antibiotic effectiveness and an …

[HTML][HTML] Anti-biofilm inhibitory synergistic effects of combinations of essential oils and antibiotics

…, A Carocci, ML Clodoveo, F Corbo, G Fracchiolla - Antibiotics, 2020 - mdpi.com
In recent years, the increase of bacteria antibiotic- resistance has been a severe problem for
public health. A useful solution could be to join some phytochemicals naturally present in …

[HTML][HTML] Overview on innovative packaging methods aimed to increase the shelf-life of cook-chill foods

…, M Muraglia, V Fino, F Curci, G Fracchiolla… - Foods, 2021 - mdpi.com
The consumption of meals prepared, packaged, and consumed inside and outside the home
is increasing globally. This is a result of rapid changes in lifestyles as well as innovations in …

Virucidal activity of ginger essential oil against caprine alphaherpesvirus-1

…, C Catella, P Capozza, A Gentile, G Fracchiolla… - Veterinary …, 2019 - Elsevier
The emergence of alphaherpesvirus strains resistant to commonly used antiviral drugs has
prompted the research for alternative, biologically active anti-herpetic agents. Essential oils (…