Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning

P Mohapel, G Leanza, M Kokaia, O Lindvall - Neurobiology of aging, 2005 - Elsevier
Hippocampus-mediated learning enhances neurogenesis in the adult dentate gyrus (DG),
and this process has been suggested to be involved in memory formation. The hippocampus …

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease

…, C Bye, G Leanza, K Double, L Thompson, G Halliday… - Brain, 2014 - academic.oup.com
The neuropathological substrate of dementia in patients with Parkinson’s disease is still
under debate, particularly in patients with insufficient alternate neuropathology for other …

Sclerostin regulation, microarchitecture, and advanced glycation end‐products in the bone of elderly women with type 2 diabetes

…, R Strollo, C Pedone, G Leanza… - Journal of Bone and …, 2020 - Wiley Online Library
Increased circulating sclerostin and accumulation of advanced glycation end‐products (AGEs)
are two potential mechanisms underlying low bone turnover and increased fracture risk in …

Selective lesioning of the basal forebrain cholinergic system by intraventricular 192 IgG–saporin: Behavioural, biochemical and stereological studies in the rat

G Leanza, OG Nilsson, RG Wiley… - European Journal of …, 1995 - Wiley Online Library
… (BK Universal, Stockholm, Sweden) weighing 200-250 g at the time of surgery, were used.
Animals … Body weight did not differ significantly between animals, and was -26CL280 g at the …

[PDF][PDF] Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide.

A Copani, V Bruno, G Battaglia, G Leanza… - Molecular …, 1995 - Citeseer
Prolonged exposure of cultured cortical cells or cultured cerebellar granule cells to the residue
25-35 fragment of-amyloid peptide (3AP), I3AP (2535), induced neuronal apoptosis, as …

Regulation of neurotrophin and traka, trkb and trkc tyrosine kinase receptor messenger RNA expression in kindling

J Bengzon, Z Kokaia, P Ernfors, M Kokaia, G Leanza… - Neuroscience, 1993 - Elsevier
Levels of messenger RNA for nerve growth factor, brain-derived neurotrophic factor,
neurotrophin-3, and the tyrosine kinase receptors trakA, trkB and trkC have been studied using in …

Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system

OG Nilsson, G Leanza, C Rosenblad, DA Lappi… - …, 1992 - journals.lww.com
A monoclonal antibody to the low-affinity NGF receptor, 192 IgG, coupled to a cytotoxin,
saporin, was recently introduced as an efficient selective neurotoxin for the NGFr-bearing …

Selective immunolesioning of the basal forebrain cholinergic system disrupts short‐term memory in rats

G Leanza, J Muir, OG Nilsson, RG Wiley… - European Journal of …, 1996 - Wiley Online Library
Selective depletion of nerve growth factor receptor‐bearing neurons in the basal forebrain
cholinergic nuclei by the immunotoxin 192 IgG‐saporin offers a new and highly useful tool for …

Wharton's jelly derived mesenchymal stromal cells: Biological properties, induction of neuronal phenotype and current applications in neurodegeneration research

…, S Viventi, LV Falzacappa, MJ Quattromani, G Leanza… - Acta histochemica, 2015 - Elsevier
… A limited number of Wharton's jelly mesenchymal stromal cells belonging to both
treatment groups appeared weakly positive for the glial marker Glial Fibrillary Acid Protein (G,H), …

Risk factors for fragility fractures in type 1 diabetes

G Leanza, E Maddaloni, D Pitocco, C Conte, A Palermo… - Bone, 2019 - Elsevier
Objective To determine clinical diabetes-related risk factors for fragility fractures in type 1
diabetes (T1D). Research design and methods History of bone fragility fractures occurring after …