User profiles for G. SHEARER

Greig Shearer

Research Scientist, University of Bath
Verified email at bath.ac.uk
Cited by 2757

A TH1→ TH2 switch is a critical step in the etiology of HIV infection

M Clerici, GM Shearer - Immunology today, 1993 - cell.com
This viewpoint proposes that an imbalance in the Tul-type and TH2-type responses contributes
to the immune dysregulation associated wiib HIV infection, and that resistance to HIV …

N2-fixation in field settings: estimations based on natural 15N abundance

G Shearer, DH Kohl - Functional Plant Biology, 1986 - CSIRO Publishing
… For the method of Bremner and Keeney, we use 1 g MgO and 3 g Devarda's alloy. For the
method of Varner et al. we add 20 ml of 20% FeS04 and 20 ml saturated Ag2S04. The size of …

Modulation of Inflammation and Immunity by Cyclic AMP: Receptors for vasoactive hormones and mediators of inflammation regulate many leukocyte functions.

…, LM Lichtenstein, CS Henney, GM Shearer - Science, 1974 - science.org
… Other experiments, performed by Shearer and co-workers, Llsing the same insolubilized …
Shearer's transfer experiments produced one surprising result: If the column procedure with …

Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS

RC Gallo, SZ Salahuddin, M Popovic, GM Shearer… - science, 1984 - science.org
Peripheral blood lymphocytes from patients with the acquired immunodeficiency syndrome (AIDS)
or with signs or symptoms that frequently precede AIDS (pre-AIDS) were grown in …

T Lymphocyte-Directed Gene Therapy for ADA SCID: Initial Trial Results After 4 Years

…, AD Miller, CS Carter, T Fleisher, M Clerici, G Shearer… - Science, 1995 - science.org
… The relative frequencies of transduced BM progenitor cells were obtained by comparing the
frequency of CFU-G, CFU-GM, BFU-E, and CFU-GEMM cells in the absence and presence …

Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

…, HK Lyerly, E Gelmann, RM Blum, GM Shearer… - The Lancet, 1986 - Elsevier
… cytotoxic effector T cells, and has been absent in each of 30 untreated AIDS patients tested
so far5 (and Shearer GM, unpublished). At entry, peripheral blood cells from patient 19 did …

Defect engineering: tuning the porosity and composition of the metal–organic framework UiO-66 via modulated synthesis

GC Shearer, S Chavan, S Bordiga, S Svelle… - Chemistry of …, 2016 - ACS Publications
Presented in this paper is a deep investigation into the defect chemistry of UiO-66 when
synthesized in the presence of monocarboxylic acid modulators under the most commonly …

Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases

DR Lucey, M Clerici, GM Shearer - Clinical microbiology reviews, 1996 - Am Soc Microbiol
In the mid-1980s, Mosmann, Coffman, and their colleagues discovered that murine CD4+
helper T-cell clones could be distinguished by the cytokines they synthesized. The isolation of …

Tuned to perfection: ironing out the defects in metal–organic framework UiO-66

GC Shearer, S Chavan, J Ethiraj, JG Vitillo… - Chemistry of …, 2014 - ACS Publications
Metal− organic frameworks (MOFs) are a relatively new class of crystalline porous materials.
1 One family of these materials that has attracted considerable attention due to their high …

Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine.

…, FT Hakim, S Hieny, GM Shearer… - Journal of immunology …, 1991 - journals.aai.org
… by low speed centrifugation (70 X g for 5 min), and pelleted again at (590 X g for 10 min). The
… The resulting homogenate was then centrifuged at 590 X g for 10 min, and the supernatant …