… Interesting1 , GHB can induce a type of catalepsy in animals3 The G m receptor antagonist
NCS-… Tunnicliff G. Stimulation of mouse brain yhydroxybutyric acid transport by pyridoxal 5’…

Buspirone has been available in the United States for over four years for the treatment of
anxiety. It was anticipated this drug would offer certain advantages over the established …

1. Phenytoin has been used with much clinical success against all types of epileptiform
seizures, except petit mal epilepsy, for over 50 years. Its mechanism of action, however, is still …

Purpose The number of US medical schools offering courses in complementary and alternative
medicine (CAM) has risen sharply in recent years. This study gauged the current state of …

1. Administration of the endogenous compound γ-hydroxybutyric acid (GHB) can induce a
sleep-like state in experimental animals and, indeed, it has been used as a general …

The human erythrocyte plasma membrane is permeable to several free amino acids usually
present in the bloodstream. Seven distict routes of entry have been described which …

Clinical depression and other mood disorders are relatively common mental illnesses but
therapy for a substantial number of patients is unsatisfactory. For many years clinicians and …

The branched chain fatty acid, valproate, has a number of distinct pharmacological effects on
the central nervous system. In experimental animals it showed clear anticonvulsant activity, …

The clinically important antidepressant fluoxetine is established as a selective serotonin
reuptake inhibitor. This study demonstrates that fluoxetine also interacts with the GABA A …

Imidazole 4-acetic acid (IMA) is a naturally occurring metabolite in brain, although it is
unclear what biochemical pathways are involved in its biosynthesis and breakdown. Some …