User profiles for Gajanan P. Shelkar

Gajanan Shelkar, PhD

Postdoctoral Fellow
Verified email at tamu.edu
Cited by 669

Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats

…, NR Kotagale, MR Patel, GP Shelkar… - European journal of …, 2010 - Elsevier
Present study investigated the role of agmatine in ethanol-induced anxiolysis and withdrawal
anxiety using elevated plus maze (EPM) test in rats. The anxiolytic-like effect of ethanol …

A simple and inexpensive method to fabricate a cannula system for intracranial injections in rats and mice

DM Kokare, GP Shelkar, CD Borkar, KT Nakhate… - … of pharmacological and …, 2011 - Elsevier
INTRODUCTION: Stereotaxic administration of neuroactive agents, either in ventricles, or
targeted at specific intracranial sites, is a widely employed strategy for neurological studies in …

Region-specific expression of NMDA receptor GluN2C subunit in parvalbumin-positive neurons and astrocytes: analysis of GluN2C expression using a novel reporter …

A Ravikrishnan, PJ Gandhi, GP Shelkar, J Liu… - Neuroscience, 2018 - Elsevier
Hypofunction of NMDA receptors in parvalbumin (PV)-positive interneurons has been
proposed as a potential mechanism for cortical abnormalities and symptoms in schizophrenia. …

Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens

GP Shelkar, PJ Gandhi, J Liu, SM Dravid - Science Advances, 2022 - science.org
Cocaine-associated memories induce cravings and interfere with the ability of users to cease
cocaine use. Reducing the strength of cue-drug memories by facilitating extinction may …

GluN2D subunit in parvalbumin interneurons regulates prefrontal cortex feedforward inhibitory circuit and molecular networks relevant to schizophrenia

DY Gawande, KKS Narasimhan, GP Shelkar… - Biological …, 2023 - Elsevier
… A significant reduction in the SST puncta (∗p = .0106; unpaired t test) and SST/PV-colocalized
puncta (∗p = .0367; unpaired t test) and an increase in PV puncta (∗p = .0156; unpaired t …

Glutamate delta 1 receptor regulates autophagy mechanisms and affects excitatory synapse maturation in the somatosensory cortex

…, V Kesherwani, PS Suryavanshi, GP Shelkar… - Pharmacological …, 2022 - Elsevier
The glutamate delta family of receptors is composed of GluD1 and GluD2 and serve as
synaptic organizers. We have previously demonstrated several autism-like molecular and …

[HTML][HTML] Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a …

J Liu, GP Shelkar, LP Sarode, DY Gawande… - Neurobiology of …, 2021 - Elsevier
… Author links open overlay panel Jinxu Liu a 1 , Gajanan P. Shelkar a 1 , Lopmudra P.
Sarode b , Dinesh Y. Gawande a , Fabao Zhao c , Rasmus Praetorius Clausen c , Rajesh R. …

[HTML][HTML] Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes

GP Shelkar, R Pavuluri, PJ Gandhi, A Ravikrishnan… - Scientific Reports, 2019 - nature.com
The GluN2C-and GluN2D-containing NMDA receptors are distinct from GluN2A-and GluN2B-containing
receptors in many aspects including lower sensitivity to Mg 2+ block and lack of …

[HTML][HTML] Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity

J Liu, GP Shelkar, PJ Gandhi, DY Gawande… - Neurobiology of …, 2020 - Elsevier
… Author links open overlay panel Jinxu Liu a , Gajanan P. Shelkar a 1 , Pauravi J. Gandhi a 1
… -stimulus interval was observed between WT and KO animals [p > .876 for all intervals, Two-…

Glutamate delta-1 receptor regulates inhibitory neurotransmission in the nucleus accumbens core and anxiety-like behaviors

DY Gawande, GP Shelkar, J Liu, AD Ayala… - Molecular …, 2021 - Springer
Glutamate delta-1 receptor (GluD1) is a member of the ionotropic glutamate receptor family
expressed at excitatory synapses and functions as a synaptogenic protein by interacting with …