Immune mechanisms and the renin–angiotensin system are implicated in preeclampsia. We
investigated 25 preeclamptic patients and compared them with 12 normotensive pregnant …

Immune mechanisms and circulating mediators may be important in the pathogenesis of
preeclampsia. We review our findings on agonistic antibodies against the angiotensin II (Ang II) …

… Material preparation and data collection and analysis were performed by Gerd Wallukat,
Bettina Hohberger, Katrin Wenzel, Julia Fürst, Sarah Schulze-Rothe, Anne Wallukat, Anne-…

Background—Idiopathic dilated cardiomyopathy (IDC) frequently is a progressive disease
without causative therapy options. Following the hypothesis that in certain patients …

Agonistic autoantibodies (AABs) against G-protein-coupled receptor (GPCR) are present
mainly in diseases of the cardiovascular system or in diseases associated with cardiovascular …

Background Antibodies against HLA antigens cause refractory allograft rejection with
vasculopathy in some, but not all, patients. Methods We studied 33 kidney-transplant recipients …

A defined cultivation system was developed for the differentiation of pluripotent embryonic
stem cells of the mouse into spontaneously beating cardiomyocytes, allowing investigations of …

BACKGROUND Autoantibodies against the beta 1-adrenoceptor have been detected in the
sera of patients with idiopathic dilated cardiomyopathy (DCM). The mechanisms by which …

Background— We recently identified agonistic autoantibodies directed against the angiotensin
AT1 receptor (AT 1 -AA) in the plasma of preeclamptic women. To elucidate their role …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protect against cardiovascular
disease by largely unknown mechanisms. We tested the hypothesis that EPA and DHA …