[HTML][HTML] Dapagliflozin protects the kidney in a non-diabetic model of cardiorenal syndrome

…, E Cianflone, S Naviglio, E Conte, GM Camerino… - Pharmacological …, 2023 - Elsevier
Cardiorenal syndrome encompasses a spectrum of disorders involving heart and kidney
dysfunction, and sharing common risk factors, such as hypertension and diabetes. Clinical …

Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests

…, A Liantonio, GM Camerino… - Journal of applied …, 2009 - journals.physiology.org
The phosphodiesterases inhibitor pentoxifylline gained attention for Duchenne muscular
dystrophy therapy for its claimed anti-inflammatory, antioxidant, and antifibrotic action. A recent …

Fluvastatin and atorvastatin affect calcium homeostasis of rat skeletal muscle fibers in vivo and in vitro by impairing the sarcoplasmic reticulum/mitochondria Ca2+ …

…, GM Camerino, S Pierno, DC Camerino - … of Pharmacology and …, 2007 - ASPET
The mechanism by which the 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins)
induce skeletal muscle injury is still under debate. By using fura-2 cytofluorimetry on intact …

Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin‐induced cachexia

E Conte, GM Camerino, A Mele… - Journal of cachexia …, 2017 - Wiley Online Library
Background Cachexia is a wasting condition associated with cancer types and, at the same
time, is a serious and dose‐limiting side effect of cancer chemotherapy. Skeletal muscle loss …

[HTML][HTML] Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and …

…, M De Bellis, E Conte, S Pierno, GM Camerino… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Muscle fibers lacking dystrophin undergo a long-term alteration of Ca 2+ homeostasis,
partially caused by a leaky Ca 2+ release ryanodine (RyR) channel. S48168/ARM210, an RyR …

Gene expression in mdx mouse muscle in relation to age and exercise: aberrant mechanical–metabolic coupling and implications for pre-clinical studies in Duchenne …

GM Camerino, M Cannone, A Giustino… - Human molecular …, 2014 - academic.oup.com
Weakness and fatigability are typical features of Duchenne muscular dystrophy patients and
are aggravated in dystrophic mdx mice by chronic treadmill exercise. Mechanical activity …

GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy

…, C Jagerschmidt, F Namour, GM Camerino… - Pharmacological …, 2013 - Elsevier
Anabolic drugs may counteract muscle wasting and dysfunction in Duchenne muscular
dystrophy (DMD); however, steroids have unwanted side effects. We focused on GLPG0492, a …

The KATP channel is a molecular sensor of atrophy in skeletal muscle

D Tricarico, A Mele, GM Camerino… - The Journal of …, 2010 - Wiley Online Library
The involvement of ATP‐sensitive K + (K ATP ) channels in the atrophy of slow‐twitch (MHC‐I)
soleus (SOL) and fast‐twitch (MHC‐IIa) flexor digitorum brevis (FDB) muscles was …

[HTML][HTML] Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia

…, JA Fehrentz, J Martinez, C Musicco, GM Camerino… - Scientific Reports, 2017 - nature.com
Chemotherapy can cause cachexia, which consists of weight loss associated with muscle
atrophy. The exact mechanisms underlying this skeletal muscle toxicity are largely unknown …

Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points

…, M De Bellis, GM Camerino… - Journal of applied …, 2017 - journals.physiology.org
Progressive weakness is a typical feature of Duchenne muscular dystrophy (DMD) patients
and is exacerbated in the benign mdx mouse model by in vivo treadmill exercise. We …