2-Aralkynyl and 2-heteroalkynyl derivatives of adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists

G Cristalli, E Camaioni, S Vittori, R Volpini… - Journal of medicinal …, 1995 - ACS Publications
A series of new 2-aralkynyl and 2-heteroaralkynyl derivatives of NECA were synthesized and
studied in binding and functional assays to assess their potency for the A2a compared to …

Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity

G Cristalli, S Vittori, A Eleuteri, M Grifantini… - Journal of medicinal …, 1991 - ACS Publications
A series of 6-(hydroxylamino) purine and-1-deazapurine nucleosides were synthesized and
tested for their antitumor and adenosine deaminase inhibitory activity. All theexamined …

Synthesis and antitumor activity of 2-. beta.-D-ribofuranosyloxazole-4-carboxamide (oxazofurin)

P Franchetti, G Cristalli, M Grifantini… - Journal of medicinal …, 1990 - ACS Publications
Condensation of 3, 4, 6-tri-0-benzoyl-2, 5-anhydro-D-allonyl chloride (4) with ethyl 2-amino-2-cyanoacetate
(5) provided 2-[(3,, 4', 6'-tri-0-benzoyl-2,, 5,-anhydroallonyl) amino]-2-…

Adenosine deaminase: functional implications and different classes of inhibitors

G Cristalli, S Costanzi, C Lambertucci… - Medicinal research …, 2001 - Wiley Online Library
Adenosine deaminase (ADA) is an enzyme of the purine metabolism which catalyzes the
irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, …

Determination of ink photoinitiators in packaged beverages by gas chromatography–mass spectrometry and liquid chromatography–mass spectrometry

G Sagratini, G Caprioli, G Cristalli, D Giardiná… - … of Chromatography A, 2008 - Elsevier
A new analytical method, using gas chromatography–mass spectrometry (GC/MS) and
liquid chromatography–mass spectrometry (LC/MS) techniques, was developed for the …

Comparative study of aroma profile and phenolic content of Montepulciano monovarietal red wines from the Marches and Abruzzo regions of Italy using HS-SPME …

G Sagratini, F Maggi, G Caprioli, G Cristalli… - Food Chemistry, 2012 - Elsevier
Montepulciano is one of the most famous and important red-berried grapes of Italy. This article
presents and discusses a comparative study of aroma profile and phenolic content of the …

2-Chloro-N6-[3H]cyclopentyladenosine ([3HCCPA) —a high affinity agonist radioligand for A1 adenosine receptors

KN Klotz, MJ Lohse, U Schwabe, G Cristalli… - Naunyn-Schmiedeberg's …, 1989 - Springer
The tritiated analogue of 2-chloro-N 6 -cyclopentyladenosine (CCPA), an adenosine derivative
with subnanomolar affinity and a 10000-fold selectivity for A 1 adenosine receptors, has …

2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors

MJ Lohse, KN Klotz, U Schwabe, G Cristalli… - Naunyn-Schmiedeberg's …, 1988 - Springer
2-Chloro-N 6 -cyclopentyladenosine (CCPA) was synthesized as a potential high affinity ligand
for A 1 adenosine receptors. Binding of [ 3 H]PIA to A 1 receptors of rat brain membranes …

Optimization of espresso machine parameters through the analysis of coffee odorants by HS-SPME–GC/MS

G Caprioli, M Cortese, G Cristalli, F Maggi, L Odello… - Food Chemistry, 2012 - Elsevier
The aroma profile and the final quality of espresso coffee (EC) are influenced by such technical
conditions as the EC machine extraction temperature and the pressure used. The effect …

Photoaffinity labeling of A1-adenosine receptors.

KN Klotz, G Cristalli, M Grifantini, S Vittori… - Journal of Biological …, 1985 - Elsevier
The ligand-binding subunit of the A1-adenosine receptor has been identified by
photoaffinity labeling. A photolabile derivative of R-N6-phenylisopropyladenosine, R-2-azido-N6-p-…