De‐racemization of enantiomers versus de‐epimerization of diastereomers—classification of dynamic kinetic asymmetric transformations (DYKAT)
J Steinreiber, K Faber, H Griengl - Chemistry–A European …, 2008 - Wiley Online Library
… enantiomeric diester I R I R and meso-isomer (I S I R ) mainly depends on the epimerization
rate of H S I R and H R I R (k 1 ) versus the anti-Kazlauskas acylation rate of H S I R (k 2 ). …
rate of H S I R and H R I R (k 1 ) versus the anti-Kazlauskas acylation rate of H S I R (k 2 ). …
Oxidative biotransformations using oxygenases
…, WA Duetz, A Schmid, A de Raadt, H Griengl… - Current opinion in …, 2002 - Elsevier
… The volumetric productivity reached 0.45 g/l/h, which is slightly higher than that of the in vivo
… The volumetric productivity reached 0.20 g/l/h, representing the first synthetic application of …
… The volumetric productivity reached 0.20 g/l/h, representing the first synthetic application of …
The synthesis of chiral cyanohydrins by oxynitrilases
H Griengl, H Schwab, M Fechter - Trends in biotechnology, 2000 - cell.com
Enantiomerically pure cyanohydrins are important synthetic intermediates for pharmaceuticals
and agrochemicals. They are produced by enzyme-catalysed synthesis using oxynitrilases…
and agrochemicals. They are produced by enzyme-catalysed synthesis using oxynitrilases…
High-level intracellular expression of hydroxynitrile lyase from the tropical rubber TreeHevea brasiliensisin microbial hosts
…, J Lückl, H Griengl, SD Kohlwein, H Schwab - Protein expression and …, 1997 - Elsevier
… with a limiting glycerol feed of 160 g/h for 24 h. Hnl production was induced by replacing
glycerol 1% BSA for 1 h. Polyclonal antiserum against Hnl from H. brasiliensis (8) was used at a …
glycerol 1% BSA for 1 h. Polyclonal antiserum against Hnl from H. brasiliensis (8) was used at a …
[PDF][PDF] A biocatalytic Henry reaction-the hydroxynitrile lyase from Hevea brasiliensis also catalyzes nitroaldol reactions
…, K Waich, W Skranc, D Mink, H Griengl - … EDITION IN ENGLISH …, 2006 - researchgate.net
… required to perform nitroaldol reactions and reach acceptable yields within 48 h. Regarding
the scope of the reaction with respect to the carbonyl acceptor, several representative …
the scope of the reaction with respect to the carbonyl acceptor, several representative …
[PDF][PDF] Biocatalytic Friedel–Crafts Alkylation Using Non‐natural Cofactors
…, P Remler, H Schwab, H Griengl… - Angewandte …, 2009 - graz.elsevierpure.com
… We observed quantitative conversion in less than 2 days (average reaction time 24 h; Table
1). The chemical synthesis of SAM analogues results in approximately 1: 1 diastereomeric …
1). The chemical synthesis of SAM analogues results in approximately 1: 1 diastereomeric …
Relation between depression and anxiety in dystonic patients: implications for clinical management
…, A Wimmer, T Wenzel, P Birner, H Griengl… - Depression and …, 2002 - Wiley Online Library
Past clinical research has identified depression as the most common psychiatric disorder
associated with cervical dystonia (CD). The purpose of our study is to document different …
associated with cervical dystonia (CD). The purpose of our study is to document different …
Threonine aldolases—an emerging tool for organic synthesis
…, F van Assema, M Wolberg, D Mink, H Griengl - Tetrahedron, 2007 - Elsevier
… as in a higher analytical yield (79%) after 4 h. Rising the temperature to 20 and 30 C resulted
in a … No similar effects were detected for lTA at temperatures below 40 C and after 2 h the …
in a … No similar effects were detected for lTA at temperatures below 40 C and after 2 h the …
Potential and capabilities of hydroxynitrile lyases as biocatalysts in the chemical industry
…, W Skranc, C Schuster, H Griengl - Applied microbiology and …, 2007 - Springer
The application of hydroxynitrile lyases (HNLs) as catalysts for the stereoselective condensation
of HCN with carbonyl compounds has been reported as early as 1908. This enzymatic C…
of HCN with carbonyl compounds has been reported as early as 1908. This enzymatic C…
[HTML][HTML] Molecular Cloning of the Full-length cDNA of (S)-Hydroxynitrile Lyase from Hevea brasiliensis: FUNCTIONAL EXPRESSION IN ESCHERICHIA COLI AND …
…, M Hayn, H Griengl, SD Kohlwein, H Schwab - Journal of Biological …, 1996 - ASBMB
… 8-10 h, plates were overlaid with a nylon filter soaked in 10 mM isopropyl-1-thio-β-D-galactopyranoside,
and expression from the lac promoter was induced by incubation for 3 h. Filters …
and expression from the lac promoter was induced by incubation for 3 h. Filters …