Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases

HP Ammon - Wiener Medizinische Wochenschrift (1946), 2002 - europepmc.org
Preparations from the gum resin of Boswellia serrata have been used as a traditional remedy
in Ayurvedic medicine in India for the treatment of inflammatory diseases. Compounds from …

[PDF][PDF] Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase.

…, MI Anazodo, LR Subramanian, HP Ammon - … of Pharmacology and …, 1992 - Citeseer
Isomers (a-and fi-) of boswellic acids (BAs), 11-keto-3-BA and In Contrast to the redox type 5-LO
inhibitor nordihydroguaiaretic their acetyl derivatives were isolated from the gum resin …

Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study.

…, S Gupta, R Lüdtke, H Safayhi, HP Ammon - European journal of …, 1998 - europepmc.org
The gum resin of Boswellia serrata, known in Indian Ayurvedic system of medicine as Salai
guggal, contains boswellic acids, which have been shown to inhibit leukotriene biosynthesis. …

Effects of Boswellia serrata gum resin in patients with ulcerative colitis.

…, R Lüdtke, H Safayhi, HP Ammon - European journal of …, 1997 - europepmc.org
Ulcerative colitis is a chronic inflammatory disease of the colon where leukotrienes are
suggested to play an important role for keeping inflammation active. Boswellic acids, the …

Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid.

H Safayhi, ER Sailer, HP Ammon - Molecular pharmacology, 1995 - ASPET
The formation of 5-lipoxygenase (EC 1.13.11.34) products from endogenous substrate by
intact rat neutrophilic granulocytes and from exogenous arachidonic acid by rat granulocyte …

Acetyl-11-keto-beta-boswellic acid (AKBA): structure requirements for binding and 5-lipoxygenase inhibitory activity.

…, B Rall, RF Hoernlein, HP Ammon… - British journal of …, 1996 - ncbi.nlm.nih.gov
5-Lipoxygenase (5-LOX) products from endogenous arachidonic acid in ionophore-stimulated
peritoneal polymorphonuclear leukocytes (PMNL) and from exogenous substrate (20 …

Adaptation of blood pressure to continuous heavy coffee drinking in young volunteers. A double‐blind crossover study.

HP Ammon, PR Bieck, D Mandalaz… - British journal of …, 1983 - Wiley Online Library
In a double‐blind crossover trial, the effect of 4 week daily ingestion of eight cups of regular
coffee (corresponding to 504 mg caffeine) vs eight cups of decaffeinated coffee was studied. …

Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis.

…, M Wehrmann, U Vogel, HP Ammon - Arzneimittel …, 1998 - europepmc.org
Mixed acetylboswellic acids, pentacyclic triterpenes extracted from the gum resin of Boswellia
serrata Roxb., significantly inhibited the ionophore-stimulated release of the leukotrienes (…

Evidence for presence of insulin receptors in rat islets of Langerhans.

EJ Verspohl, HP Ammon - The Journal of clinical …, 1980 - Am Soc Clin Investig
Binding of insulin to islets of Langerhans was studied. It was found that "specific" binding of [125I]insulin
("specific" binding equals total binding minus nonspecific binding) was …

Increase in glucose consumption by acetylcysteine during hyperglycemic clamp. A study with healthy volunteers.

HP Ammon, PH Müller, M Eggstein… - Arzneimittel …, 1992 - europepmc.org
Thiols have been shown to be related to insulin secretion and to uptake of glucose into
tissues. In the present study the effects of iv administration of acetylcysteine (N-acetylcysteine, …