User profiles for H. Drechsler

Hauke Drechsler

University of Tübingen, D
Verified email at mechanochemistry.org
Cited by 391

Osteoporotic fracture risk associated with cumulative exposure to tenofovir and other antiretroviral agents

R Bedimo, NM Maalouf, S Zhang, H Drechsler, P Tebas - Aids, 2012 - journals.lww.com
Background: Whereas tenofovir (TDF) exposure has been associated with decreased bone
density, it remains unclear whether it is associated with increased risk of osteoporotic …

Gilbert syndrome and the development of antiretroviral therapy–associated hyperbilirubinemia

…, H Furrer, P Vernazza, H Drechsler… - The Journal of …, 2005 - academic.oup.com
BackgroundUnconjugated hyperbilirubinemia results from Gilbert syndrome and from
antiretroviral therapy (ART) containing protease inhibitors. An understanding of the interaction …

Switching effective antiretroviral therapy: a review

KH Mayer, H Drechsler… - Clinical Infectious …, 2002 - academic.oup.com
One approach to target the long-term metabolic toxicity and disfiguring body-shape changes
associated with antiretroviral therapy is to switch one component of a regimen to an …

Exotic mitotic mechanisms

H Drechsler, AD McAinsh - Open biology, 2012 - royalsocietypublishing.org
The emergence of eukaryotes around two billion years ago provided new challenges for the
chromosome segregation machineries: the physical separation of multiple large and linear …

Abacavir use and risk of acute myocardial infarction and cerebrovascular events in the highly active antiretroviral therapy era

RJ Bedimo, AO Westfall, H Drechsler… - Clinical Infectious …, 2011 - academic.oup.com
(See the editorial commentary by Bozzette on pages 92–93 .) Background. Some studies
have suggested that exposure to antiretroviral therapy (ART) with abacavir is associated with …

Hepatitis c virus coinfection and the risk of cardiovascular disease among hiv‐infected patients

…, AO Westfall, M Mugavero, H Drechsler… - HIV …, 2010 - Wiley Online Library
Background Among HIV‐infected patients, hepatitis C virus (HCV) coinfection is associated
with lower cholesterol levels, but it remains unclear how it affects cardiovascular outcomes. …

[PDF][PDF] Mps1 regulates kinetochore-microtubule attachment stability via the Ska complex to ensure error-free chromosome segregation

J Maciejowski, H Drechsler, K Grundner-Culemann… - Developmental cell, 2017 - cell.com
… 18 h later, 1 mg/ml aphidicolin was added for 12 h to synchronize cells in early S phase.
Cells were then washed with PBS and cultured for another 13 h in fresh SILAC medium …

[HTML][HTML] Skin disease prevalence study in schoolchildren in rural Cote d'Ivoire: Implications for integration of neglected skin diseases (skin NTDs)

…, LC Fuller, R Hay, O Mitjà, H Drechsler… - PLoS neglected …, 2018 - journals.plos.org
Background Early detection of several skin-related neglected tropical diseases (skin NTDs)–including
leprosy, Buruli ulcer, yaws, and scabies- may be achieved through school surveys…

[HTML][HTML] The RADAR study: week 48 safety and efficacy of RAltegravir combined with boosted DARunavir compared to tenofovir/emtricitabine combined with boosted …

RJ Bedimo, H Drechsler, M Jain, J Cutrell, S Zhang… - PloS one, 2014 - journals.plos.org
Background NRTI-sparing regimens may avoid long-term mitochondrial, bone and renal
toxicities and maintain viral suppression. Methods In the RADAR study, 85 antiretroviral-naïve …

The Kinesin-12 Kif15 is a processive track-switching tetramer

H Drechsler, T McHugh, MR Singleton, NJ Carter… - Elife, 2014 - elifesciences.org
Drechsler et al. have isolated individual Kif15 motor proteins and used advanced microscopy
techniques to study them in action. These experiments showed that Kif15 motor proteins …