The SLC22 drug transporter family

H Koepsell, H Endou - Pflügers Archiv, 2004 - Springer
… Excretion across the sinuosoidal membrane into the bile is mediated by an as yet
unidentified polyspecific H + /organic cation antiporter and/or by P-glycoprotein MDR1 [25, 26]. …

CATs and HATs: the SLC7 family of amino acid transporters

F Verrey, EI Closs, CA Wagner, M Palacin, H Endou… - Pflügers Archiv, 2004 - Springer
The SLC7 family is divided into two subgroups, the cationic amino acid transporters (the
CAT family, SLC7A1–4) and the glycoprotein-associated amino acid transporters (the gpaAT …

Molecular physiology of urate transport

…, RJ Johnson, H Miyazaki, H Endou - Physiology, 2005 - journals.physiology.org
Humans excrete uric acid as the final breakdown product of unwanted purine nucleotides.
Urate scavenges potential harmful radicals in our body. However, in conjunction with genetic …

Molecular identification of a renal urate–anion exchanger that regulates blood urate levels

…, T Hosoya, K Shimokata, T Niwa, Y Kanai, H Endou - Nature, 2002 - nature.com
… oocytes was measured for 1 h in the presence or absence of … -expressing and control oocytes
for 16–24 h at 16 C in a Cl - -… 1 h in the 0 Cl - bath. All data are mean ± sem with n = 8–10. …

[HTML][HTML] Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

…, K Miyamoto, H Uchino, E Takeda, H Endou - Journal of Biological …, 1998 - ASBMB
… The third lane shows the products in the presence of microsomes after deglycosylation with
endoglycosidase H. Translation of LAT1 and 4F2hc cRNAs in the absence of microsomes …

[HTML][HTML] Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines

…, K Miyamoto, E Takeda, T Goya, H Endou - … et Biophysica Acta (BBA …, 2001 - Elsevier
System L is a major nutrient transport system responsible for the transport of large neutral
amino acids including several essential amino acids. We previously identified a transporter (L-…

[HTML][HTML] Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity

…, Y Fukasawa, K Miyamoto, E Takeda, H Endou… - Journal of Biological …, 1999 - ASBMB
We have isolated a cDNA from rat small intestine that encodes a novel Na + -independent
neutral amino acid transporter with distinctive characteristics in substrate selectivity and …

[HTML][HTML] Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain

…, SH Cha, Y Sugiyama, Y Kanai, H Endou - Journal of Biological …, 1999 - ASBMB
… with unlabeled substrates for 5 h and then transferred into the medium containing [ 3 H]estrone
sulfate (40 nm). The uptake rate of [ 3 H]estrone sulfate for 1 h was determined. …

Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney

…, Y Kanai, Y Kobayashi, T Goya, H Endou - Molecular …, 2001 - ASPET
… The cell-associated count of [ 3 H]estrone sulfate increased linearly until 3 h of incubation
in hOAT3-expressing oocytes. This result indicates that hOAT3 not only binds but also …

[HTML][HTML] Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

…, DK Kim, Y Sugiyama, Y Kanai, H Endou - Journal of Biological …, 2000 - ASBMB
… of [ 3 H]estrone sulfate, [ 3 H]dehydroepiandrosterone sulfate (DHEA-s), and [ 3 H]ochratoxin …
The cell-associated count of [ 3 H]estrone sulfate increased linearly until 2.5 h of incubation …