Naturally arising CD25 + CD4 + regulatory T (Treg) cells, most of which are produced by the
normal thymus as a functionally mature T‐cell subpopulation, play key roles in the …

Mesenchymal stem cell (MSC) transplantation has been explored as a new clinical approach
to repair injured tissue. A growing corpus of studies have highlighted two important aspects …

… the other hand, approximately half of congenital atypical haemolytic uremic syndrome (aHUS)
cases are caused by genetic mutations in complement regulatory factors, such as factor H, …

A transcription factor, Cbfa1, which belongs to the runt-domain gene family, is expressed
restrictively in fetal development. To elucidate the function of Cbfa1, we generated mice with a …

CD44 is an adhesion molecule expressed in cancer stem-like cells. Here, we show that a
CD44 variant (CD44v) interacts with xCT, a glutamate-cystine transporter, and controls the …

… (A–H) Representative staining patterns of serous adenocarcinomas with grade 3 (B and F),
grade 2 (C and G), and grade 0 (D and H) expression of PD-L1 (B–D) and PD-L2 (F–H) are …

… (a–e) Representative images of ischemic rat livers during decellularization process at 0 h
(a), 18 h (b), 48 h (c), 52 h (d) and 72 h (e). The livers were perfused through the portal vein …

… H Yagi and Y Furutani contributed equally to this investigation: H Yagi did the sequence
analysis and analysed the patients' data including clinical details. Y Furutani did FISH analysis …

… A total of 1.0 × 10 4 sorted T cells with 2.0 × 10 4 APC were cultured (0.2 ml per well, U-bottomed
96-well plate) for 96 h in the presence of soluble anti-CD3 mAb (20 ng ml −1 ; HIT3a). [ …

… To block endogenous peroxidase activity, all sections were treated with 100% methanol
containing 0.3% H 2 O 2 for 15 minutes. Nonspecific binding of immunoglobulin G was blocked …