User profiles for Hibah O. Awwad

Hibah O. Awwad

Clinical Assistant Professor, University of Oklahoma Health Sciences Center
Verified email at ouhsc.edu
Cited by 182

Alzheimer's Disease-Related Dementias Summit 2022: national research priorities for the investigation of post-traumatic brain injury Alzheimer's disease and related …

K Dams-O'Connor, HO Awwad, S Hoffman… - Journal of …, 2023 - liebertpub.com
Traumatic Brain Injury (TBI) is a risk factor for Alzheimer's disease and Alzheimer's disease
related dementias (AD/ADRD) and otherwise classified post-traumatic neurodegeneration (…

Cellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ

CL Donica, HO Awwad, DR Thakker… - Molecular pharmacology, 2013 - ASPET
The nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor is the fourth and most recently
discovered member of the opioid receptor superfamily that also includes μ, δ, and κ opioid …

Therapeutic potential of nociceptin/orphanin FQ peptide (NOP) receptor modulators for treatment of traumatic brain injury, traumatic stress, and their co-morbidities

ON Al Yacoub, HO Awwad, Y Zhang… - Pharmacology & …, 2022 - Elsevier
The nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor is a member of the opioid
receptor superfamily with N/OFQ as its endogenous agonist. Wide expression of the NOP …

[HTML][HTML] Blast overpressure waves induce transient anxiety and regional changes in cerebral glucose metabolism and delayed hyperarousal in rats

HO Awwad, LP Gonzalez, P Tompkins, M Lerner… - Frontiers in …, 2015 - frontiersin.org
Physiological alterations, anxiety, and cognitive disorders are strongly associated with blast-induced
traumatic brain injury (blast TBI), and are common symptoms in service personnel …

[HTML][HTML] TMPRSS2- Driven ERG Expression In Vivo Increases Self-Renewal and Maintains Expression in a Castration Resistant Subpopulation

…, PL Martin, HS Tillman, G Petrovics, HO Awwad… - 2012 - journals.plos.org
Genomic rearrangements commonly occur in many types of cancers and often initiate or
alter the progression of disease. Here we describe an in vivo mouse model that recapitulates …

[PDF][PDF] Recovery from traumatic brain injury (TBI) is Nociceptin/Orphanin FQ peptide (NOP) receptor genotype-, sex-, and injury severity-dependent

ON Al Yacoub, HO Awwad… - J. Pharmacol. Exp …, 2023 - pdfs.semanticscholar.org
Traumatic brain injury (TBI) is a leading cause of death and disability in the United States
and survivors often experience mental and physical health consequences that reduce quality …

Post-blast treatment with Nociceptin/Orphanin FQ peptide (NOP) receptor antagonist reduces brain injury-induced hypoxia and signaling proteins in vestibulomotor …

HO Awwad, CD Durand, LP Gonzalez… - Behavioural brain …, 2018 - Elsevier
Mild traumatic brain injury (mTBI) diagnoses have increased due to aggressive sports and
blast-related injuries, but the cellular mechanisms and pathology underlying mTBI are not …

Orphanin FQ/nociceptin activates nuclear factor kappa B

CL Donica, VI Ramirez, HO Awwad, NT Zaveri… - Journal of Neuroimmune …, 2011 - Springer
Endogenous neuropeptide orphanin FQ/nociceptin (OFQ/N) and its receptor, nociceptin
orphanin FQ peptide receptor (NOPr), play a modulatory role throughout the body including …

Inhibitors of phosphoinositide 3-kinase cause defects in the postendocytic sorting of β2-adrenergic receptors

HO Awwad, V Iyer, JL Rosenfeld, EE Millman… - Experimental cell …, 2007 - Elsevier
Phosphatidylinositol 3-kinase inhibitors have been shown to affect endocytosis or
subsequent intracellular sorting in various receptor systems. Agonist-activated β 2 -adrenergic …

Mutating the dileucine motif of the human β2-adrenoceptor reduces the high initial rate of receptor phosphorylation by GRK without affecting postendocytic sorting

HO Awwad, EE Millman, E Alpizar-Foster… - European journal of …, 2010 - Elsevier
The internalization of β 2 -adrenoceptors after agonist activation results in a desensitized and
phosphorylated receptor that either resensitizes by recycling to the cell surface or becomes …