Background & Aims: Tumor necrosis factor (TNF)-α is associated with increased mortality in
alcoholics, but its role in early alcohol-induced liver injury is not fully understood. Recently, it …

In North America, liver disease due to alcohol consumption is an important cause of death
in adults, although its pathogenesis remains obscure. Despite the fact that resident hepatic …

Tumor necrosis factor (TNF)α, a pivotal cytokine involved in inflammation, is produced primarily
by Kupffer cells in the liver. It has been shown that inactivation of Kupffer cells prevents …

A metallographical investigation of manganess-aluminum system was made in the compositional
range of 47% to 60% of manganese, with the results of a new hexagonal close-packed …

Considerable evidence for a role of Kupffer cells in alcoholic liver disease has accumulated
and they have recently been shown to be a predominant source of free radicals. Several …

OBJECTIVE: The purpose of this study was to characterize the etching behavior of titanium in
concentrated sulfuric acid and discuss its application on surface modification of titanium for …

Postoperative pancreatic fistula (POPF) is one of the most severe complications after
pancreatic surgeries. POPF develops as a consequence of pancreatic juice leakage from a …

Background & Aims: Ethanol causes both tolerance and sensitization of Kupffer cells. This
study was designed to evaluate temporal effects of ethanol in an attempt to understand this …

The oxidant source in alcohol-induced liver disease remains unclear. NADPH oxidase (mainly
in liver Kupffer cells and infiltrating neutrophils) could be a potential free radical source. …

The occurrence of malignant tumors of the upper gastrointestinal tract and liver is, based
largely on epidemiological evidence, causally related to the consumption of ethanol. It is widely …