User profiles for Hongbo Cai
Hongbo CaiUniveristy of Pittsburgh Verified email at pitt.edu Cited by 74 |
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
…, G Yang, Y Zhang, OA Balbin, S Barbe, H Cai… - Nature medicine, 2015 - nature.com
Profiling candidate therapeutics with limited cancer models during preclinical development
hinders predictions of clinical efficacy and identifying factors that underlie heterogeneous …
hinders predictions of clinical efficacy and identifying factors that underlie heterogeneous …
Stem cell characteristics of amniotic epithelial cells
Amniotic epithelial cells develop from the epiblast by 8 days after fertilization and before
gastrulation, opening the possibility that they might maintain the plasticity of pregastrulation …
gastrulation, opening the possibility that they might maintain the plasticity of pregastrulation …
Induction of leptin resistance through direct interaction of C-reactive protein with leptin
K Chen, F Li, J Li, H Cai, S Strom, A Bisello… - Nature medicine, 2006 - nature.com
The mechanisms underlying leptin resistance are still being defined. We report here the
presence in human blood of several serum leptin-interacting proteins (SLIPs), isolated by leptin-…
presence in human blood of several serum leptin-interacting proteins (SLIPs), isolated by leptin-…
[HTML][HTML] Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450
…, BJ Komoroski, R Venkataramanan, H Cai… - Journal of Biological …, 2001 - ASBMB
Sister of P-glycoprotein (SPGP) is the major hepatic bile salt export pump (BSEP). BSEP/SPGP
expression varies dramatically among human livers. The potency and hierarchy of bile …
expression varies dramatically among human livers. The potency and hierarchy of bile …
Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures
BJ Komoroski, S Zhang, H Cai, JM Hutzler… - Drug metabolism and …, 2004 - ASPET
St. John's wort extract (SJW) (Hypericum perforatum L.) is among the most commonly used
herbal medications in the United States. The predominance of clinical reports indicates that …
herbal medications in the United States. The predominance of clinical reports indicates that …
Household pathway selection of energy consumption during urbanization process in China
C Sun, X Ouyang, H Cai, Z Luo, A Li - Energy Conversion and Management, 2014 - Elsevier
China’s growing energy demand is driven by urbanization. Facing the problem of energy
scarcity, residential energy consumption is a crucial area of energy conservation and …
scarcity, residential energy consumption is a crucial area of energy conservation and …
The state's role and position in international trade: A complex network perspective
Y Fan, S Ren, H Cai, X Cui - Economic Modelling, 2014 - Elsevier
Based on statistical physics and graph theory, the research paradigm of a complex network,
which has sprung up in the last decade, provides us with new global perspective to discuss …
which has sprung up in the last decade, provides us with new global perspective to discuss …
A new look at the remittances-FDI-energy-environment nexus in the case of selected Asian nations
This study investigates the association between remittances, FDI, energy use, and CO 2
emissions for a sample of the top six Asian nations receiving remittances, namely, China, India, …
emissions for a sample of the top six Asian nations receiving remittances, namely, China, India, …
Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats
…, K Rose, J Burliegh, P Zocharski, H Cai… - Toxicological …, 2003 - academic.oup.com
Inhibition of canalicular bile acid efflux by medications is associated with clinical liver toxicity,
sometimes in the absence of major liver effects in experimental species. To predict the …
sometimes in the absence of major liver effects in experimental species. To predict the …
[HTML][HTML] The Atacama Cosmology Telescope: A measurement of the DR6 CMB lensing power spectrum and its implications for structure growth
We present new measurements of cosmic microwave background (CMB) lensing over 9400
deg 2 of the sky. These lensing measurements are derived from the Atacama Cosmology …
deg 2 of the sky. These lensing measurements are derived from the Atacama Cosmology …