User profiles for Hongbo Cai

Hongbo Cai

Univeristy of Pittsburgh
Verified email at pitt.edu
Cited by 74

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

…, G Yang, Y Zhang, OA Balbin, S Barbe, H Cai… - Nature medicine, 2015 - nature.com
Profiling candidate therapeutics with limited cancer models during preclinical development
hinders predictions of clinical efficacy and identifying factors that underlie heterogeneous …

Stem cell characteristics of amniotic epithelial cells

T Miki, T Lehmann, H Cai, DB Stolz, SC Strom - Stem cells, 2005 - academic.oup.com
Amniotic epithelial cells develop from the epiblast by 8 days after fertilization and before
gastrulation, opening the possibility that they might maintain the plasticity of pregastrulation …

Induction of leptin resistance through direct interaction of C-reactive protein with leptin

K Chen, F Li, J Li, H Cai, S Strom, A Bisello… - Nature medicine, 2006 - nature.com
The mechanisms underlying leptin resistance are still being defined. We report here the
presence in human blood of several serum leptin-interacting proteins (SLIPs), isolated by leptin-…

[HTML][HTML] Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450

…, BJ Komoroski, R Venkataramanan, H Cai… - Journal of Biological …, 2001 - ASBMB
Sister of P-glycoprotein (SPGP) is the major hepatic bile salt export pump (BSEP). BSEP/SPGP
expression varies dramatically among human livers. The potency and hierarchy of bile …

Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

BJ Komoroski, S Zhang, H Cai, JM Hutzler… - Drug metabolism and …, 2004 - ASPET
St. John's wort extract (SJW) (Hypericum perforatum L.) is among the most commonly used
herbal medications in the United States. The predominance of clinical reports indicates that …

Household pathway selection of energy consumption during urbanization process in China

C Sun, X Ouyang, H Cai, Z Luo, A Li - Energy Conversion and Management, 2014 - Elsevier
China’s growing energy demand is driven by urbanization. Facing the problem of energy
scarcity, residential energy consumption is a crucial area of energy conservation and …

The state's role and position in international trade: A complex network perspective

Y Fan, S Ren, H Cai, X Cui - Economic Modelling, 2014 - Elsevier
Based on statistical physics and graph theory, the research paradigm of a complex network,
which has sprung up in the last decade, provides us with new global perspective to discuss …

A new look at the remittances-FDI-energy-environment nexus in the case of selected Asian nations

ZU Rahman, H Cai, M Ahmad - The Singapore Economic Review, 2023 - World Scientific
This study investigates the association between remittances, FDI, energy use, and CO 2
emissions for a sample of the top six Asian nations receiving remittances, namely, China, India, …

Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats

…, K Rose, J Burliegh, P Zocharski, H Cai… - Toxicological …, 2003 - academic.oup.com
Inhibition of canalicular bile acid efflux by medications is associated with clinical liver toxicity,
sometimes in the absence of major liver effects in experimental species. To predict the …

[HTML][HTML] The Atacama Cosmology Telescope: A measurement of the DR6 CMB lensing power spectrum and its implications for structure growth

…, E Biermann, B Bolliet, JR Bond, H Cai… - The Astrophysical …, 2024 - iopscience.iop.org
We present new measurements of cosmic microwave background (CMB) lensing over 9400
deg 2 of the sky. These lensing measurements are derived from the Atacama Cosmology …