Quantum dot 705, a cadmium-based nanoparticle, induces persistent inflammation and granuloma formation in the mouse lung

CC Ho, H Chang, HT Tsai, MH Tsai, CS Yang… - …, 2013 - Taylor & Francis
Some quantum dots (QDs) have been applied for drug delivery and imaging in biological
systems. Drug delivery via the lung and lung imaging are potential applications of QDs. QD705 …

Particulate nature of inhaled zinc oxide nanoparticles determines systemic effects and mechanisms of pulmonary inflammation in mice

…, H Chang, JF Lin, CS Yang, MH Tsai, HT Tsai… - …, 2015 - Taylor & Francis
Inhalation of zinc oxide nanoparticles (ZnONP) has potential health impact. Because zinc ion
may involve in the toxicity of ZnONP, we compared adverse effects of inhaled aerosolized …

Involvement of MyD88 in zinc oxide nanoparticle-induced lung inflammation

…, CC Ho, CS Yang, WH Chang, MH Tsai, HT Tsai… - Experimental and …, 2013 - Elsevier
Zinc oxide nanoparticles (ZnONP) have great potential for medical applications. However,
ZnONP is reported to induce acute lung inflammation, which limits its application in humans. …

Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes

…, MT Chiang, L Chang, YC Kuo, HT Tsai… - Food and chemical …, 2009 - Elsevier
To investigate whether diabetes-induced alterations of CYP2E1 and oxidative stress can be
modulated by dietary taurine supplementation, male Wistar rats were divided into non-…

Involvement of Oxidative Stress and Activation of Aryl Hydrocarbon Receptor in Elevation of CYP1A1 Expression and Activity in Lung Cells and Tissues by Arsenic: An In Vitro …

…, HT Yao, H Chang, HT Tsai, MH Tsai… - Toxicological …, 2009 - academic.oup.com
Epidemiological evidence indicated that there was a synergistic interaction between arsenic
and cigarette smoke on enhancement of lung cancer risk. Benzo[a]pyrene (B[a]P), a …

Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: effects of size and particulate nature

…, MY Wang, WH Chang, MH Tsai, HT Tsai… - …, 2012 - iopscience.iop.org
Although zinc oxide nanoparticles (ZnONPs) have been applied in nanotechnology, their
kinetics and tissue distribution in vivo are unknown. Here we compared the kinetics and tissue …

[HTML][HTML] Ambient particulate matter induces vascular smooth muscle cell phenotypic changes via NOX1/ROS/NF-κB dependent and independent pathways: Protective …

CC Ho, YC Chen, MH Tsai, HT Tsai, CY Weng, SF Yet… - Antioxidants, 2021 - mdpi.com
Epidemiological studies have demonstrated an association between ambient particulate
matter (PM) exposure and vascular diseases. Here, we observed that treatment with ambient …

[HTML][HTML] Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and …

…, WT Wu, YJ Lin, CY Weng, MH Tsai, HT Tsai… - Particle and Fibre …, 2022 - Springer
Background Exposure to ambient fine particulate matter (PM 2.5 ) is associated with
vascular diseases. Polycyclic aromatic hydrocarbons (PAHs) in PM 2.5 are highly hazardous; …

Interleukin-24 as a target cytokine of environmental aryl hydrocarbon receptor agonist exposure in the lung

YH Luo, YC Kuo, MH Tsai, CC Ho, HT Tsai… - Toxicology and applied …, 2017 - Elsevier
Exposure to environmental aryl hydrocarbon receptor (AhR) agonists, such as halogenated
aromatic hydrocarbons and polycyclic aromatic hydrocarbons (PAHs), has great impacts on …

Identification of ambient fine particulate matter components related to vascular dysfunction by analyzing spatiotemporal variations

CC Ho, YC Chen, SF Yet, CY Weng, HT Tsai… - Science of the total …, 2020 - Elsevier
Exposure to ambient fine particulate matter (PM 2.5 ) has been associated with vascular
diseases in epidemiological studies. We have demonstrated previously that exposure to …