Activation of the aryl hydrocarbon receptor (AHR) by agonists and environmental contaminants
like dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) leads to many adverse biological effects, …

Conventional genetic approaches have provided a powerful tool in the study of proteins.
However, these techniques often preclude selective manipulation of temporal and spatial …

Estrogen receptor‐α (ER) antagonists have been widely used for breast cancer therapy.
Despite initial responsiveness, hormone‐sensitive ER‐positive cancer cells eventually develop …

The quest for developing anticancer principles from natural sources has a long historical
track record and remarkable success stories. The pungent principle of hot chili pepper, …

Small molecules designed to specifically activate or inactivate protein functions have been
useful to study biological processes. PROTACS are small molecule chimera which comprise …

Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates
genes involved in drug/xenobiotic metabolism, cell cycle progression, cell fate determination, …

3-Deoxysappanchalcone (3-DSC) has been reported to possess anti-allergic, antiviral, anti-inflammatory
and antioxidant activities. In the present study, we investigated the effects of 3-…

Non-destructive stress measurement by ultrasonic testing is based on calculating the
acoustoelastic modulus obtained from the relationship between material stress and sound wave …

Kaurane diterpene compounds have been known to be cytotoxic against several cancer cells
through inhibition of nuclear factor-κB (NF-κB) activity. Here, we showed that inflexinol, a …

Non-destructive stress measurement using ultrasonic techniques is based on calculation of
the acoustoelastic coefficient obtained from the relationship between material stress and …