[HTML][HTML] Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve, …
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve, …
A systematic review of sensory-based treatments for children with disabilities
Sensory-based therapies are designed to address sensory processing difficulties by helping
to organize and control the regulation of environmental sensory inputs. These treatments …
to organize and control the regulation of environmental sensory inputs. These treatments …
Development of a college transition and support program for students with autism spectrum disorder
Empirically based, consumer-informed programming to support students with Autism Spectrum
Disorder (ASD) transitioning to college is needed. Informed by theory and research, the …
Disorder (ASD) transitioning to college is needed. Informed by theory and research, the …
[HTML][HTML] A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs, and
disease states are connected by virtue of common gene-expression signatures. Here, we …
disease states are connected by virtue of common gene-expression signatures. Here, we …
A layered hybrid perovskite solar‐cell absorber with enhanced moisture stability
Two‐dimensional hybrid perovskites are used as absorbers in solar cells. Our first‐generation
devices containing (PEA) 2 (MA) 2 [Pb 3 I 10 ] (1; PEA=C 6 H 5 (CH 2 ) 2 NH 3 + , MA=CH …
devices containing (PEA) 2 (MA) 2 [Pb 3 I 10 ] (1; PEA=C 6 H 5 (CH 2 ) 2 NH 3 + , MA=CH …
MONARCH 3: abemaciclib as initial therapy for advanced breast cancer
Purpose Abemaciclib, a cyclin-dependent kinase 4 and 6 inhibitor, demonstrated efficacy as
monotherapy and in combination with fulvestrant in women with hormone receptor (HR)–…
monotherapy and in combination with fulvestrant in women with hormone receptor (HR)–…
MONARCH 2: abemaciclib in combination with fulvestrant in women with HR+/HER2− advanced breast cancer who had progressed while receiving endocrine therapy
Purpose MONARCH 2 ( ClinicalTrials.gov identifier: NCT02107703) compared the efficacy
and safety of abemaciclib, a selective cyclin-dependent kinase 4 and 6 inhibitor, plus …
and safety of abemaciclib, a selective cyclin-dependent kinase 4 and 6 inhibitor, plus …
Neoadjuvant chemotherapy in breast cancer: significantly enhanced response with docetaxel
PURPOSE: To compare the efficacy of neoadjuvant (NA) docetaxel (DOC) with anthracycline-based
therapy and determine the efficacy of NA DOC in patients with breast cancer initially …
therapy and determine the efficacy of NA DOC in patients with breast cancer initially …
Abemaciclib combined with endocrine therapy for the adjuvant treatment of HR+, HER2−, node-positive, high-risk, early breast cancer (monarchE)
PURPOSE Many patients with HR+, HER2− early breast cancer (EBC) will not experience
recurrence or have distant recurrence with currently available standard therapies. However, …
recurrence or have distant recurrence with currently available standard therapies. However, …
Positron Emission Tomography Using [18F]-Fluorodeoxy-d-Glucose to Predict the Pathologic Response of Breast Cancer to Primary Chemotherapy
IC Smith, AE Welch, AW Hutcheon, ID Miller… - Journal of Clinical …, 2000 - ascopubs.org
PURPOSE: To determine whether [ 18 F]-fluorodeoxy-d-glucose ([ 18 F]-FDG) positron emission
tomography (PET) can predict the pathologic response of primary and metastatic breast …
tomography (PET) can predict the pathologic response of primary and metastatic breast …