Eating a “Westernized” diet high in fat and sugar leads to weight gain and numerous health
problems, including the development of type 2 diabetes mellitus (T2DM). Rodent studies …

Therapeutics aimed at blocking the cannabinoid 1 (CB1) receptor for treatment of obesity
resulted in significant improvements in liver function, glucose uptake and pancreatic β-cell …

Aims/hypothesis The cannabinoid 1 receptor (CB1R) regulates insulin sensitivity and
glucose metabolism in peripheral tissues. CB1R is expressed on pancreatic beta cells and is …

The cannabinoid 1 receptor (CB1) is an important regulator of energy metabolism. Reports
of in vivo and in vitro studies give conflicting results regarding its role in insulin secretion, …

The study of the components of mitochondrial metabolism has potential benefits for health
span and lifespan because the maintenance of efficient mitochondrial function and antioxidant …

Coenzyme Q 10 (CoQ 10 ) is a redox molecule critical for the proper function of energy
metabolism and antioxidant defenses. Despite its essential role in cellular metabolism, the …

Background and Aims: The synthetic atypical cannabinoid Abn-CBD, a cannabidiol (CBD)
derivative, has been recently shown to modulate the immune system in different organs, but …

Sarcopenic obesity, the combination of skeletal muscle mass and function loss with an
increase in body fat, is associated with physical limitations, cardiovascular diseases, metabolic …

Coenzyme Q (CoQ) is an isoprenylated benzoquinone found in mitochondria, which functions
mainly as an electron carrier from complex I or II to complex III in the inner membrane. …

The mechanisms regulating incretin secretion are not fully known. Human obesity is associated
with altered incretin secretion and elevated endocannabinoid levels. Since cannabinoid …