[HTML][HTML] Zika virus promotes neuronal cell death in a non-cell autonomous manner by triggering the release of neurotoxic factors
IG Olmo, VV Costa, J Alves-Silva, CZ Ferrari… - Frontiers in …, 2017 - frontiersin.org
Zika virus (ZIKV) has recently caused a worldwide outbreak of infections associated with
severe neurological complications, including microcephaly in infants born from infected mothers…
severe neurological complications, including microcephaly in infants born from infected mothers…
Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide
Zika virus is a mosquito-borne virus that is associated with neurodegenerative diseases,
including Guillain–Barré syndrome 1 and congenital Zika syndrome 2 . As Zika virus targets the …
including Guillain–Barré syndrome 1 and congenital Zika syndrome 2 . As Zika virus targets the …
N-Methyl-d-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection
Zika virus (ZIKV) infection is a global health emergency that causes significant neurodegeneration.
Neurodegenerative processes may be exacerbated by N-methyl-d-aspartate receptor …
Neurodegenerative processes may be exacerbated by N-methyl-d-aspartate receptor …
N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease
FR Silva, AS Miranda, RPM Santos, IG Olmo… - Neurobiology of …, 2017 - Elsevier
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused
by a polyglutamine expansion in the amino-terminal region of the huntingtin (htt) protein. In …
by a polyglutamine expansion in the amino-terminal region of the huntingtin (htt) protein. In …
Alterations of Calcium Channels in a Mouse Model of Huntington's Disease and Neuroprotection by Blockage of CaV1 Channels
…, PL Cardozo, FR Silva, JM de Souza, IG Olmo… - ASN …, 2019 - journals.sagepub.com
Huntington’s disease (HD) is a neurodegenerative autosomal dominant disorder, characterized
by symptoms of involuntary movement of the body, loss of cognitive function, psychiatric …
by symptoms of involuntary movement of the body, loss of cognitive function, psychiatric …
The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington's disease
…, JM de Souza, FR Silva, IG Olmo… - Journal of …, 2018 - Wiley Online Library
Huntington's Disease (HD) is an autosomal‐dominant neurodegenerative disorder, characterized
by involuntary body movements, cognitive impairment, and psychiatric disorder. The …
by involuntary body movements, cognitive impairment, and psychiatric disorder. The …
Dissecting the signaling pathways involved in the crosstalk between metabotropic glutamate 5 and cannabinoid type 1 receptors
IG Olmo, TH Ferreira-Vieira, FM Ribeiro - Molecular Pharmacology, 2016 - ASPET
The metabotropic glutamate 5 receptor and the cannabinoid type 1 receptor are G protein–coupled
receptors that are widely expressed in the central nervous system. Metabotropic …
receptors that are widely expressed in the central nervous system. Metabotropic …
[HTML][HTML] mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington's disease phenotype
…, EMA Maciel, NC Silva, IBQ Lima, JG Doria, IG Olmo… - Scientific Reports, 2022 - nature.com
Glutamate receptors, including mGluR5, are involved in learning and memory impairments
triggered by aging and neurological diseases. However, each condition involves distinct …
triggered by aging and neurological diseases. However, each condition involves distinct …
High-throughput sequencing of BACHD mice reveals upregulation of neuroprotective miRNAs at the pre-symptomatic stage of Huntington's disease
Huntington’s disease (HD) is a genetic disorder marked by transcriptional alterations that
result in neuronal impairment and death. MicroRNAs (miRNAs) are non-coding RNAs involved …
result in neuronal impairment and death. MicroRNAs (miRNAs) are non-coding RNAs involved …
Role of dynein axonemal heavy chain 6 gene expression as a possible biomarker for Huntington's disease: a translational study
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized
by motor dysfunction, cognitive deficits, and psychiatric symptoms. The primary genetic …
by motor dysfunction, cognitive deficits, and psychiatric symptoms. The primary genetic …