User profiles for Isabella G. Olmo

Isabella Guimarães Olmo

- Verified email at unistra.fr - Cited by 1939

Isabella Guimarães Olmo

- Verified email at unistra.fr - Cited by 406

[HTML][HTML] Zika virus promotes neuronal cell death in a non-cell autonomous manner by triggering the release of neurotoxic factors

IG Olmo, VV Costa, J Alves-Silva, CZ Ferrari… - Frontiers in …, 2017 - frontiersin.org
Zika virus (ZIKV) has recently caused a worldwide outbreak of infections associated with
severe neurological complications, including microcephaly in infants born from infected mothers…

Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide

…, JH Park, PL Cardozo, AR Ferhan, IG Olmo… - Nature Materials, 2018 - nature.com
Zika virus is a mosquito-borne virus that is associated with neurodegenerative diseases,
including Guillain–Barré syndrome 1 and congenital Zika syndrome 2 . As Zika virus targets the …

N-Methyl-d-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection

…, JL Del Sarto, RF Rocha, FR Silva, JG Doria, IG Olmo… - MBio, 2017 - Am Soc Microbiol
Zika virus (ZIKV) infection is a global health emergency that causes significant neurodegeneration.
Neurodegenerative processes may be exacerbated by N-methyl-d-aspartate receptor …

N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease

FR Silva, AS Miranda, RPM Santos, IG Olmo… - Neurobiology of …, 2017 - Elsevier
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused
by a polyglutamine expansion in the amino-terminal region of the huntingtin (htt) protein. In …

Alterations of Calcium Channels in a Mouse Model of Huntington's Disease and Neuroprotection by Blockage of CaV1 Channels

…, PL Cardozo, FR Silva, JM de Souza, IG Olmo… - ASN …, 2019 - journals.sagepub.com
Huntington’s disease (HD) is a neurodegenerative autosomal dominant disorder, characterized
by symptoms of involuntary movement of the body, loss of cognitive function, psychiatric …

The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington's disease

…, JM de Souza, FR Silva, IG Olmo… - Journal of …, 2018 - Wiley Online Library
Huntington's Disease (HD) is an autosomal‐dominant neurodegenerative disorder, characterized
by involuntary body movements, cognitive impairment, and psychiatric disorder. The …

Dissecting the signaling pathways involved in the crosstalk between metabotropic glutamate 5 and cannabinoid type 1 receptors

IG Olmo, TH Ferreira-Vieira, FM Ribeiro - Molecular Pharmacology, 2016 - ASPET
The metabotropic glutamate 5 receptor and the cannabinoid type 1 receptor are G protein–coupled
receptors that are widely expressed in the central nervous system. Metabotropic …

[HTML][HTML] mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington's disease phenotype

…, EMA Maciel, NC Silva, IBQ Lima, JG Doria, IG Olmo… - Scientific Reports, 2022 - nature.com
Glutamate receptors, including mGluR5, are involved in learning and memory impairments
triggered by aging and neurological diseases. However, each condition involves distinct …

High-throughput sequencing of BACHD mice reveals upregulation of neuroprotective miRNAs at the pre-symptomatic stage of Huntington's disease

IG Olmo, RP Olmo, ANA Gonçalves, RGW Pires… - ASN …, 2021 - journals.sagepub.com
Huntington’s disease (HD) is a genetic disorder marked by transcriptional alterations that
result in neuronal impairment and death. MicroRNAs (miRNAs) are non-coding RNAs involved …

Role of dynein axonemal heavy chain 6 gene expression as a possible biomarker for Huntington's disease: a translational study

LB Areal, LP Pereira, FM Ribeiro, IG Olmo… - Journal of Molecular …, 2017 - Springer
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized
by motor dysfunction, cognitive deficits, and psychiatric symptoms. The primary genetic …