User profiles for J A Saugstad

Julie Saugstad

Oregon Health & Science University
Verified email at ohsu.edu
Cited by 13044

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

…, A Saftics, US Sandau, JA Saugstad… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration

JA Saugstad - Journal of Cerebral Blood Flow & Metabolism, 2010 - journals.sagepub.com
MicroRNAs are small RNAs that function as regulators of posttranscriptional gene expression.
MicroRNAs are encoded by genes, and processed to form ribonucleoprotein complexes …

[PDF][PDF] The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research

…, MS Sabatine, NA Sakhanenko, JA Saugstad… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

[HTML][HTML] miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132

…, G Mouri, K Tanaka, T Sano, JA Saugstad… - The American journal of …, 2011 - Elsevier
When an otherwise harmful insult to the brain is preceded by a brief, noninjurious stimulus,
the brain becomes tolerant, and the resulting damage is reduced. Epileptic tolerance …

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels

…, WZ Wang, XM Zhu, JA Saugstad… - Journal of …, 2004 - Soc Neuroscience
Acid-sensing ion channels (ASICs), a novel class of ligand-gated cation channels activated
by protons, are highly expressed in peripheral sensory and central neurons. Activation of …

Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex

…, J Lan, RP Simon, JA Saugstad - Journal of Cerebral …, 2010 - journals.sagepub.com
Preconditioning describes the ischemic stimulus that triggers an endogenous, neuroprotective
response that protects the brain during a subsequent severe ischemic injury, a …

Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile

JA Saugstad, JM Kinzie, MM Shinohara… - Molecular …, 1997 - ASPET
The metabotropic glutamate receptor (mGluR) cDNAs were originally cloned from rat,
except for the mouse cDNA clone encoding mGluR8. Mouse mGluR8 couples weakly to the …

Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors.

JA Saugstad, JM Kinzie, ER Mulvihill, TP Segerson… - Molecular …, 1994 - ASPET
Despite the cloning of several metabotropic glutamate receptors (mGluR1-6), the activity
and localization of the cloned mGluRs do not account for the action of L-2-amino-4-…

RGS4 inhibits signaling by group I metabotropic glutamate receptors

JA Saugstad, MJ Marino, JA Folk… - Journal of …, 1998 - Soc Neuroscience
Metabotropic glutamate receptors (mGluRs) couple to heterotrimeric G-proteins and
regulate cell excitability and synaptic transmission in the CNS. Considerable effort has been …

MicroRNAs in human cerebrospinal fluid as biomarkers for Alzheimer's disease

…, JA Lapidus, JF Quinn, JA Saugstad - Journal of …, 2017 - content.iospress.com
Background: Currently available biomarkers of Alzheimer’s disease (AD) include cerebrospinal
fluid (CSF) protein analysis and amyloid PET imaging, each of which has limitations. The …