The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …

Addiction can be viewed as a form of drug-induced neural plasticity. One of the best-established
molecular mechanisms of addiction is upregulation of the cAMP second messenger …

Objectives: To summarize new knowledge surrounding the physiological activity of
tocotrienol, a natural analogue of tocopherol. Results: The biological activity of vitamin E has …

Gastric cancer is the third leading cause of cancer-related deaths worldwide. Over 95% of
gastric cancers are adenocarcinomas, which are typically classified based on anatomic …

Background Dupilumab is a fully human anti–interleukin-4 receptor α monoclonal antibody
that blocks both interleukin-4 and interleukin-13 signaling. We assessed its efficacy and …

The rapid disruption of tropical forests probably imperils global biodiversity more than any
other contemporary phenomenon 1 , 2 , 3 . With deforestation advancing quickly, protected …

During the solar wind dynamic pressure enhancement, around 0200 UT on January 11,
1997, at the end of the January 6–11 magnetic cloud event, the magnetopause was pushed …

Background Dupilumab is a fully human anti–interleukin-4 receptor α monoclonal antibody
that blocks both interleukin-4 and interleukin-13 signaling. Its effectiveness in reducing oral …

Gastric cancer is the fifth most frequently diagnosed cancer and the third leading cause of
death from cancer in the world. Several advances have been made in the staging procedures, …

The ability to perform long, accurate molecular dynamics (MD) simulations involving proteins
and other biological macro-molecules could in principle provide answers to some of the …