Glutamate, nitric oxide and cell-cell signalling in the nervous system

J Garthwaite - Trends in neurosciences, 1991 - cell.com
… John Garthwaite John Garthwaite is at the Department of Physiology, University of Liverpool…
and Garthwaite, J., unpublished observations). At central glutamatergic synapses, the NO …

Excitatory amino acid neurotoxicity and neurodegenerative disease

B Meldrum, J Garthwaite - Trends in pharmacological sciences, 1990 - cell.com
… In this article Brian Meldrum and John Garthwaite review in vivo and in vitro studies of the
cytotoxicity of amino acids and summarize the contribution of such toxicity to acute and chronic …

Nitric oxide signaling in the central nervous system

J Garthwaite, CL Boulton - Annual review of physiology, 1995 - annualreviews.org
… guanylyl cyclase enzyme (J Garthwaite et aI, submitted) should greatly assist progress. …
East SJ, Garthwaite J. 1991. NMDA receptor activation in rat hippocampus induces cyclic …

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

J Garthwaite, SL Charles, R Chess-Williams - Nature, 1988 - nature.com
In the vascular system, endothelium-derived relaxing factor (EDRF) is the name of the local
hormone released from endothelial cells in response to vasodilators such as acetylcholine, …

NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices

J Garthwaite, G Garthwaite, RMJ Palmer… - European journal of …, 1989 - Elsevier
… The amounts of cGMP and protein in each slice were determined using radioimmunoassay
and the automated Lowry method respectively (see Garthwaite and Garthwaite, 1987 for …

[PDF][PDF] Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1, 2, 4] oxadiazolo [4, 3-a] quinoxalin-1-one.

J Garthwaite, E Southam, CL Boulton, EB Nielsen… - Molecular …, 1995 - Citeseer
In brain and other tissues, nitric oxide (NO) operates as a diffusible second messenger that
stimulates the soluble form of the guanylyl cyclase enzyme and so elicits an accumulation of …

Concepts of neural nitric oxide‐mediated transmission

J Garthwaite - European Journal of Neuroscience, 2008 - Wiley Online Library
… to the many talented people whom I have been fortunate to have in my laboratory doing the
research on NO signalling, the most long-standing (and long-suffering) being Giti Garthwaite. …

Models of the diffusional spread of nitric oxide: implications for neural nitric oxide signalling and its pharmacological properties

J Wood, J Garthwaite - Neuropharmacology, 1994 - Elsevier
Nitric oxide (NO) functions as a diffusible messenger molecule in many different tissues,
including the brain. To create a conceptual framework for understanding the behaviour of NO in …

The concise guide to pharmacology 2019/20: Enzymes

…, A Friebe, J Garthwaite, J Gertsch… - British Journal of …, 2019 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …

[HTML][HTML] What is the real physiological NO concentration in vivo?

CN Hall, J Garthwaite - Nitric oxide, 2009 - Elsevier
… rate is calculated to be about 1 s −1 when the geometry of the capillary circulation is taken
into consideration and assuming that any NO entering a capillary is lost (Wood and Garthwaite