Multiplicity of mechanisms of serotonin receptor signal transduction

JR Raymond, YV Mukhin, A Gelasco, J Turner… - Pharmacology & …, 2001 - Elsevier
The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into 7 subfamilies
by convention, 6 of which include 13 different genes for G-protein-coupled receptors. Those …

The recombinant 5‐HT1A receptor: G protein coupling and signalling pathways

JR Raymond, YV Mukhin, TW Gettys… - British journal of …, 1999 - Wiley Online Library
… John R Raymond … John R Raymond … ) the National Institutes of Health (DK52448
and DK53981 to JR Raymond and TW Gettys), the US Department of Agriculture (NRICGP/USDA …

The renal dopamine receptors.

PA Jose, JR Raymond, MD Bates… - Journal of the …, 1992 - journals.lww.com
Dopamine is an endogenous catecholamine that modulates many functions including behavior,
movement, nerve conduction, hormone synthesis and release, blood pressure, and ion …

The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

A Fargin, JR Raymond, MJ Lohse, BK Kobilka… - Nature, 1988 - nature.com
… (JR Raymond et al., in preparation). A peptide from another portion of the G-21 protein (amino
acids 268–293: SKAGGALCANGAVRFGGAALEVIE) was used in these experiments to …

Prevention of hemodialysis fistula thrombosis. Early detection of venous stenoses

SJ Schwab, JR Raymond, M Saeed, GE Newman… - Kidney international, 1989 - Elsevier
Prevention of hemodialysis fistula thrombosis. Early detection of venous stenoses. Venous
dialysis pressures were measured consecutively in 168 chronic hemodialysis patients for 265 …

[HTML][HTML] Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and …

MG Eason, H Kurose, BD Holt, JR Raymond… - Journal of Biological …, 1992 - Elsevier
Coupling of the three alpha 2-adrenergic receptor (alpha 2AR) subtypes to Gi and Gs was
studied in membranes from transfected CHO cells. We observed that in the presence of low …

Urine biomarkers predict the cause of glomerular disease

…, JC Oates, JR Raymond… - Journal of the …, 2007 - journals.lww.com
Diagnosis of the type of glomerular disease that causes the nephrotic syndrome is necessary
for appropriate treatment and typically requires a renal biopsy. The goal of this study was to …

Effector coupling mechanisms of the cloned 5-HT1A receptor

A Fargin, JR Raymond, JW Regan, S Cotecchia… - Journal of Biological …, 1989 - ASBMB
The signal transduction pathways of the cloned human 5-HT1A receptor have been examined
in two mammalian cell lines transiently (COS-7) or permanently (HeLa) expressing this …

Serotonin 5-HT2A receptor induces TGF-β1 expression in mesangial cells via ERK: proliferative and fibrotic signals

…, MN Garnovskaya, JR Raymond… - American Journal …, 1999 - journals.physiology.org
… of Veterans Affairs Merit Awards (to JR Raymond and MN Garnovskaya), National Institutes
of Health Grants DK-52448 and HL-03710 (to JR Raymond and EL Greene), a laboratory …

[HTML][HTML] Serotonin 5-HT1A receptor-mediated Erk activation requires calcium/calmodulin-dependent receptor endocytosis

…, LM Luttrell, RJ Lefkowitz, JR Raymond - Journal of Biological …, 1999 - ASBMB
Many receptors that couple to heterotrimeric guanine nucleotide-binding (G) proteins
mediate rapid activation of the mitogen-activated protein kinases, Erk1 and Erk2. The G i -coupled …