[HTML][HTML] Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations
for the definition of distinct cell death morphologies and for the appropriate use of cell …
for the definition of distinct cell death morphologies and for the appropriate use of cell …
Autophagy in major human diseases
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
Caspases in apoptosis and beyond
J Li, J Yuan - Oncogene, 2008 - nature.com
The demonstration of protein sequence and functional homology of the Caenorhabditis
elegans programmed cell death gene product, CED-3, with human caspase-1 in 1993 triggered …
elegans programmed cell death gene product, CED-3, with human caspase-1 in 1993 triggered …
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
…, J Chen, Y Meng, J Wang, Y Lin, J Yuan, Z Xie, J Ma… - The lancet, 2020 - thelancet.com
Background In late December, 2019, patients presenting with viral pneumonia due to an
unidentified microbial agent were reported in Wuhan, China. A novel coronavirus was …
unidentified microbial agent were reported in Wuhan, China. A novel coronavirus was …
[HTML][HTML] Antibody responses to SARS-CoV-2 in patients with COVID-19
…, F Zhang, P Liu, J Yuan, Q Li, JL Hu, J Chen… - Nature medicine, 2020 - nature.com
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within
19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G …
19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G …
[HTML][HTML] Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
Different types of cell death are often defined by morphological criteria, without a clear
reference to precise biochemical mechanisms. The Nomenclature Committee on Cell Death (…
reference to precise biochemical mechanisms. The Nomenclature Committee on Cell Death (…
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Immune checkpoint inhibitors, which unleash a patient’s own T cells to kill tumors, are
revolutionizing cancer treatment. To unravel the genomic determinants of response to this therapy, …
revolutionizing cancer treatment. To unravel the genomic determinants of response to this therapy, …
SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler
…, J Yuan, G He, Y Chen, Q Pan, Y Liu, J Tang… - …, 2012 - academic.oup.com
Background There is a rapidly increasing amount of de novo genome assembly using next-generation
sequencing (NGS) short reads; however, several big challenges remain to be …
sequencing (NGS) short reads; however, several big challenges remain to be …
Prognostic determinants for chronic hepatitis B in Asians: therapeutic implications
Background: Identifying risk factors for the development of complications of chronic hepatitis
B (CHB) is important for setting up treatment criteria. Aim: To determine risk factors for the …
B (CHB) is important for setting up treatment criteria. Aim: To determine risk factors for the …
[HTML][HTML] Genetic basis for clinical response to CTLA-4 blockade in melanoma
Background Immune checkpoint inhibitors are effective cancer treatments, but molecular
determinants of clinical benefit are unknown. Ipilimumab and tremelimumab are antibodies …
determinants of clinical benefit are unknown. Ipilimumab and tremelimumab are antibodies …