Magnetic resonance spectroscopy is increasingly used as a non-invasive method to investigate
apoptosis. Apoptosis was induced in Jurkat T-cells by Fas mAb. 1 H magnetic resonance …

Our aim was to determine whether biological molecular markers can predict response to
neoadjuvant chemoendocrine therapy in patients with early breast cancer. Ninety patients (…

Background A tumour-bed boost delivered after whole-breast radiotherapy increases local
cancer-control rates but requires more patient visits and can increase breast hardness. …

Wild-type p53 is frequently mutated in late-stage ovarian cancer and has been proposed as
a determinant of cisplatin chemosensitivity. We have therefore established a human ovarian …

Aim: To determine the effects of tamoxifen on the levels of hormone receptors and proliferation
markers in the early phase of treatment and the relationship of the changes with tumor …

Background IMPORT HIGH is a randomised, multi-centre phase III trial testing dose escalated
simultaneous integrated boost (SIB) against sequential boost each delivered by intensity …

Purpose/Objective IMPORT HIGH is a randomised phase 3 trial testing dose escalated
simultaneous integrated boost (SIB) against sequential boost using intensity modulated …

An oestrogen sensitive rat mammary tumour was grown in two groups of female and one
group of male hooded rats. The male group and one of the female groups were supplemented …

The P53gene is frequently mutated in late stage ovarian cancer and has been proposed as
a determinant of radiation and chemosensitivity. We have therefore determined the p53 …

This study was undertaken to evaluate our abilityto detect multiple molecular markers of
prognosis andresponse to treatment in fine needle aspirates (FNA)from patients with primary …