Intestinal myofibroblasts are α-smooth muscle actin-positive stromal cells that exist as a
syncytium with fibroblasts and mural cells in the lamina propria of the gut. Through expression …

Ischemia/reperfusion (I/R) injury induces both functional and morphological changes in the
kidney. Necrosis, predominantly of the proximal tubule (PT), is the hallmark of this model of …

The human gastrointestinal mucosa is exposed to a diverse normal microflora and dietary
Ags and is a common site of entry for pathogens. The mucosal immune system must respond …

Elevated mucosal interleukin-1 (IL-1) levels are frequently seen during acute and chronic
intestinal inflammation, and IL-1 neutralization lessens the severity of inflammation. One major …

Purpose: Recent data support the hypothesis that the inducible isoform of cyclooxygenase (COX-2)
plays a role in the early stages of colonic carcinogenesis and that nonsteroidal anti-…

Ribosome stalling in the leader region of ermC mRNA results in a 10–15‐fold increase in
ermC mRNA half‐life in Bacillus subtilis. Fusion of the ermC 5′ regulatory region to several B. …

Context.—Myofibroblasts are distinct cells with characteristics of both smooth muscle cells
and fibroblasts. Through their ability to secrete cytokines, chemokines, prostaglandins, growth …

Externally triggered signaling pathways allow cells to adapt to their environment through
diverse cellular responses. In a given milieu, depending on cell and stimulus specificity, the …

Food poisoning due to staphylococcal enterotoxins A and B (SEA and SEB) affects
hundreds of thousands of people annually. SEA and SEB induce massive intestinal cytokine …

BACKGROUND & AIMS:: Intestinal myofibroblasts (IMFs) express cyclooxygenase 2 (COX-2)
early on in polyp progression and respond to pro-inflammatory cytokines. Interleukin (IL)-…