Measuring nicotinic receptors with characteristics of α4β2, α3β2 and α3β4 subtypes in rat tissues by autoradiography
…, Y Xiao, HN Nguyen, JL Musachio… - Journal of …, 2002 - Wiley Online Library
Abstract Comparison of [ 125 I]epibatidine and 5‐[ 125 I]iodo‐3‐(2‐azetidinylmethoxy)pyridine
([ 125 I]A‐85380) autoradiography showed evidence for nicotinic receptor heterogeneity. …
([ 125 I]A‐85380) autoradiography showed evidence for nicotinic receptor heterogeneity. …
11C-MCG: Synthesis, Uptake Selectivity, and Primate PET of a Probe for Glutamate Carboxypeptidase II (NAALADase)
MG Pomper, JL Musachio, J Zhang… - Molecular …, 2002 - journals.sagepub.com
Imaging of glutamate carboxypeptidase II (GCP II), also known as N-acetylated α-linked l-amino
dipeptidase (NAALADase), may enable study of glutamatergic transmission, prostate …
dipeptidase (NAALADase), may enable study of glutamatergic transmission, prostate …
PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements
…, JS Liow, J Shah, JL Musachio… - Journal of Nuclear …, 2006 - Soc Nuclear Med
18 F-2β-Carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl)nortropane ( 18 F-FECNT), a
PET radioligand for the dopamine transporter (DAT), generates a radiometabolite that enters …
PET radioligand for the dopamine transporter (DAT), generates a radiometabolite that enters …
PET imaging with [11C] PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat
…, HJ Kim, SS Zoghbi, E Briard, J Hong, JL Musachio… - Neuroscience …, 2007 - Elsevier
Peripheral benzodiazepine receptors (PBRs) are upregulated on activated microglia. We
recently developed a promising positron emission tomography (PET) ligand, [ 11 C]PBR28, …
recently developed a promising positron emission tomography (PET) ligand, [ 11 C]PBR28, …
Sazetidine-A, a novel ligand that desensitizes α4β2 nicotinic acetylcholine receptors without activating them
Y Xiao, H Fan, JL Musachio, ZL Wei… - Molecular …, 2006 - ASPET
Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels found
throughout the central and peripheral nervous systems. They are crucial to normal physiology …
throughout the central and peripheral nervous systems. They are crucial to normal physiology …
Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease
…, S Rivera, SS Zoghbi, JS Liow, JL Musachio… - Stem …, 2007 - academic.oup.com
The derivation of dopamine neurons is one of the best examples of the clinical potential of
embryonic stem (ES) cells, but the long-term function of the grafted neurons has not been …
embryonic stem (ES) cells, but the long-term function of the grafted neurons has not been …
PET imaging of brain with the β-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease
…, JS Liow, L Cai, D Jacobowitz, JL Musachio… - European journal of …, 2005 - Springer
Purpose The purpose of this study was to evaluate the capacity of [ 11 C]6-OH-BTA-1 and
positron emission tomography (PET) to quantify β-amyloid (Aβ) plaques in the Tg2576 mouse …
positron emission tomography (PET) to quantify β-amyloid (Aβ) plaques in the Tg2576 mouse …
Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652
…, M Suehiro, WB Mathews, HT Ravert, JL Musachio… - Synapse, 1995 - Wiley Online Library
This paper presents the first Positron Emission Tomography (PET) images of the serotonin (5‐hydroxytryptamine,
5‐HT) transporter in the living human brain. PET imaging was …
5‐HT) transporter in the living human brain. PET imaging was …
Syntheses of 11 C-and 18 F-labeled carboxylic esters within a hydrodynamically-driven micro-reactor
SY Lu, P Watts, FT Chin, J Hong, JL Musachio… - Lab on a Chip, 2004 - pubs.rsc.org
Carboxylic esters were successfully labeled with one of two short-lived positron-emitters,
carbon-11 or fluorine-18, within a hydrodynamically-driven micro-reactor. The non-radioactive …
carbon-11 or fluorine-18, within a hydrodynamically-driven micro-reactor. The non-radioactive …
Imaging of δ opioid receptors in human brain by N1′‐ ([11C]methyl)naltrindole and PET
…, CM Kinter, U Scheffel, HT Ravert, JL Musachio… - Synapse, 1996 - Wiley Online Library
Recently, we have developed the positron emitting radiotracer N1′-([11 C] methyl) naltrindole
([11 C] MeNTI) and demonstrated its high selectivity for δ opioid receptors in the mouse …
([11 C] MeNTI) and demonstrated its high selectivity for δ opioid receptors in the mouse …