Toxicities associated with NBOMe ingestion—a novel class of potent hallucinogens: a review of the literature

…, ES Valenti, FAA Cruz, AM Correa, JL Poklis, A Poklis - Psychosomatics, 2015 - Elsevier
Background A new class of synthetic hallucinogens called NBOMe has emerged as drugs
of abuse. Objective Our aim was to conduct a systematic review of published reports of …

Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain

…, JZ Long, ST O'Neal, RA Abdullah, JL Poklis… - … of Pharmacology and …, 2009 - ASPET
Direct-acting cannabinoid receptor agonists are well known to reduce hyperalgesic responses
and allodynia after nerve injury, although their psychoactive side effects have damped …

Postmortem detection of 25I-NBOMe [2-(4-iodo-2, 5-dimethoxyphenyl)-N-[(2-methoxyphenyl) methyl] ethanamine] in fluids and tissues determined by high …

JL Poklis, KG Devers, EF Arbefeville… - Forensic science …, 2014 - Elsevier
We present a traumatic fatality of a 19-year-old man who had ingested blotter paper
containing 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine]. …

A case of 25I-NBOMe (25-I) intoxication: a new potent 5-HT2A agonist designer drug

SR Rose, JL Poklis, A Poklis - Clinical toxicology, 2013 - Taylor & Francis
Context. Abuse of synthetic stimulant compounds resulting in significant toxicity is being
increasingly reported by poison centers. Toxicologic assessment is complicated by inconsistent …

Analysis of 25I-NBOMe, 25B-NBOMe, 25C-NBOMe and Other Dimethoxyphenyl-N-[(2-Methoxyphenyl) Methyl]Ethanamine Derivatives on Blotter Paper

JL Poklis, SA Raso, KN Alford, A Poklis… - Journal of analytical …, 2015 - academic.oup.com
In recent years, N-methoxybenzyl-methoxyphenylethylamine (NBOMe) derivatives, a class
of designer hallucinogenic drugs, have become popular drugs of abuse. These drugs have …

Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet

KM Boini, C Zhang, M Xia, JL Poklis, PL Li - Journal of Pharmacology and …, 2010 - ASPET
The present study tested a hypothesis that excess accumulation of sphingolipid, ceramide,
its metabolites, or a combination contributes to the development of obesity and associated …

Concentration of nicotine and glycols in 27 electronic cigarette formulations

…, N Smith, CE Wolf, JL Poklis, A Poklis - Journal of analytical …, 2016 - academic.oup.com
Personal battery-powered vaporizers or electronic cigarettes were developed to deliver a
nicotine vapor such that smokers could simulate smoking tobacco without the inherent …

Development of a clinically viable heroin vaccine

…, ML Banks, FF Steele, B Zhou, JL Poklis… - Journal of the …, 2017 - ACS Publications
Heroin is a highly abused opioid and incurs a significant detriment to society worldwide. In
an effort to expand the limited pharmacotherapy options for opioid use disorders, a heroin …

The unexpected identification of the cannabimimetic, 5F-ADB, and dextromethorphan in commercially available cannabidiol e-liquids

JL Poklis, HA Mulder, MR Peace - Forensic science international, 2019 - Elsevier
Electronic cigarettes (e-cigarettes) were developed as an alternative method for nicotine
delivery and had a significant surge in popularity. E-liquids are formulations used in e-cigarettes…

Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced …

…, N Patel, G Donvito, MA Mustafa, JL Poklis… - … of Pharmacology and …, 2018 - ASPET
Although paclitaxel effectively treats various cancers, its debilitating peripheral neuropathic
pain side effects often persist long after treatment has ended. Therefore, a compelling need …