The synthesis of some l, 6-dihydro-6-oxo-2-phenylpyrimidine-5-carboxylic acids and esters
with potent oral and intravenous antiallergicactivity against passive cutaneous anaphylaxis …

The 4-aminopyridines (VII) were prepared by reducing the 4-nitro-compounds (VI) with
Raney nickel and hydrazine hydrate or with iron and acetic acid, or by reducing the 4-…

Approximately 60 derivatives of anguidin were prepared for evaluation of antitumor activities.
Positions 3, 4, 8-10, and 15 were modified, and the resultant derivatives were screened …

No difficulty was encountered in converting the N-substituted G-aminopenicillanyl alcohols
into various esters, including phenylcarbainates, alkali salts of acid succinates, and acetates. …

DISCUSSION Ultraviolet data are collected in Table 1, and illustrated in Figs. 1 4. Before
these are discussed in the special context of the three classes of amine, some brief general …

The amino-acids omithine and proime have been shown to serve as precursors of the
alkaloid stachydrine in the mature 5 1 2 -6 month old alfalfa plant. Degradation of the alkaloid …

A series of derivatives of 5-methoxysterigmatocystin (3a, 12c-dihydro-8-hydroxy-6, ll-dimethoxy-7fi-furo
[3', 2': 4, 5] furo [2, 3-c] xanthen-7-one) has been prepared and evaluated for …

Some 2-(2-alkoxyphenyl)-and 2-[2-(alkenyloxy) phenyl]-5-(l/f-tetrazol-5-yl) pyrimidin-4 (3fí)-ones
were prepared and found to be about 5-10 times more potent than the corresponding …

CO.. K decarboxylated as shown by attempted recrystalliza-tion from hot EtOAc which
yielded 5-benzyltetrazole.('onsequently, modification of the carboxyl function to provide an …

Examples of the hitherto unknown penicillin aldehydes (4) have been synthesized by a novel
three-step process involving selective desulfurization of penicillin thioacid salts (2) under …