The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine

…, S El Mestikawy, M Quiroz, B Hoffman, JM Haflett… - Molecular …, 2008 - ASPET
Rxt1/NTT4 (SLC6A17) belongs to a gene family of “orphan transporters” whose substrates
and consequently functions remain unidentified. Although Rxt1/NTT4 was previously thought …

[CITATION][C] The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid vesicular transporter selective for proline, glycine, leucine, and …

…, S El Mestikawy, M Quiroz, B Hoffman, JM Haflett… - Molecular …, 2008 - ASPET
Rxt1/NTT4 (SLC6A17) belongs to a gene family of" orphan transporters" whose substrates
and consequently functions remain unidentified. While Rxt1/NTT4 was previously thought to …

[HTML][HTML] Synaptic vesicle protein NTT4/XT1 (SLC6A17) catalyzes Na+-coupled neutral amino acid transport

KA Zaia, RJ Reimer - Journal of biological chemistry, 2009 - ASBMB
The SLC6 family of structurally related, Na + -dependent transporter proteins is responsible
for presynaptic reuptake of the majority of neurotransmitters. Within this family are a number …

[HTML][HTML] The molecular chaperone Hsc70 interacts with tyrosine hydroxylase to regulate enzyme activity and synaptic vesicle localization

LA Parra, TB Baust, AD Smith, JD Jaumotte… - Journal of Biological …, 2016 - ASBMB
We previously reported that the vesicular monoamine transporter 2 (VMAT2) is physically and
functionally coupled with Hsc70 as well as with the dopamine synthesis enzymes tyrosine …

[HTML][HTML] SLC6 family transporter SNF-10 is required for protease-mediated activation of sperm motility in C. elegans

…, MC Jud, BA Duffy, JP Norton, JM Hansen… - Developmental …, 2014 - Elsevier
Motility of sperm is crucial for their directed migration to the egg. The acquisition and modulation
of motility are regulated to ensure that sperm move when and where needed, thereby …

Long-chain omega-3 fatty acids and blood pressure

JC Liu, SM Conklin, SB Manuck, JK Yao… - American journal of …, 2011 - academic.oup.com
High dose fish oil supplementation reduces blood pressure (BP) in hypertensive patients.
The current study examines how modest variations in omega-3 fatty acid intake may affect BP …

Dopamine and psychosis: theory, pathomechanisms and intermediate phenotypes

H Tost, T Alam, A Meyer-Lindenberg - Neuroscience & Biobehavioral …, 2010 - Elsevier
Schizophrenia is a chronic, severe, and disabling brain disorder arising from the adverse
interaction of predisposing risk genes and environmental factors. The psychopathology is …

Angiogenic and immune signatures in plasma of young relatives at familial high-risk for psychosis and first-episode patients: a preliminary study

PL Lizano, MS Keshavan, N Tandon, IT Mathew… - Schizophrenia …, 2016 - Elsevier
Haflett for their technical assistance and to Diana Mermon for her help in clinical assessments
of FHR subjects, and Jean Miewald for her help in data management. We thank the …

Association of sFlt-1 and worsening psychopathology in relatives at high risk for psychosis: a longitudinal study

PL Lizano, JK Yao, N Tandon, SS Mothi… - Schizophrenia …, 2017 - Elsevier
Haflett for their technical assistance and to Diana Mermon for her help in clinical assessments
of FHR subjects, and Jean Miewald for her help in data management. We thank the …

A novel role for PHT1 in the disposition of l-histidine in brain: In vitro slice and in vivo pharmacokinetic studies in wildtype and Pht1 null mice

XX Wang, Y Hu, RF Keep, N Toyama-Sorimachi… - Biochemical …, 2017 - Elsevier
PHT1 (SLC15A4) is responsible for translocating l-histidine (l-His), di/tripeptides and peptide-like
drugs across biological membranes. Previous studies have indicated that PHT1 is …