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Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway

I Kim, HG Kim, JN So, JH Kim, HJ Kwak… - Circulation …, 2000 - Am Heart Assoc
Angiopoietin-1 (Ang1) is a strong apoptosis survival factor for endothelial cells. In this study,
the receptor/second messenger signal transduction pathway for the antiapoptotic effect of …

Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion

I Kim, HG Kim, SO Moon, SW Chae, JN So… - Circulation …, 2000 - Am Heart Assoc
Angiopoietin-1 (Ang1) is a strong inducer of endothelial cell sprouting, which is a first step in
both angiogenesis and neovascularization. We examined the mechanisms underlying Ang1…

[HTML][HTML] Angiopoietin-1 is an apoptosis survival factor for endothelial cells

HJ Kwak, JN So, SJ Lee, I Kim, GY Koh - FEBS letters, 1999 - Elsevier
We examined the effect of angiopoietin-1 (Ang1) on apoptosis in human umbilical vein
endothelial cells (HUVECs). Ang1 (5–1000 ng/ml) dose-dependently inhibited apoptosis under a …

Angiogenic role of adrenomedullin through activation of Akt, mitogen‐activated protein kinase, and focal adhesion kinase in endothelial cells

…, SO Moon, MJ Sung, SH Kim, S Lee, JN So… - The FASEB …, 2003 - Wiley Online Library
Adrenomedullin (AM) is a multifunctional peptide in human pheochromocytoma. To
evaluate whether AM could be an angiogenic factor, we examined its effect on kinases and …

Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin‐3

I Kim, HJ Kwak, JE Ahn, JN So, M Liu, KN Koh… - FEBS …, 1999 - Wiley Online Library
Using homology‐based PCR, we have isolated cDNA encoding a novel member (491 amino
acids) of the angiopoietin (Ang) family from human adult heart cDNA and have designated …

Angiopoietin‐1 negatively regulates expression and activity of tissue factor in endothelial cells

I Kim, JL Oh, YS Ryu, JN So, WC Sessa… - The FASEB …, 2002 - Wiley Online Library
Normally, tissue factor (TF) is not expressed on the surface of endothelial cells, but its expression
can be induced by vascular endothelial growth factor (VEGF) and tumor necrosis factor …

Matrilysin (MMP‐7) promotes invasion of ovarian cancer cells by activation of progelatinase

F Wang, J So, S Reierstad… - International journal of …, 2005 - Wiley Online Library
Although matrilysin (MMP‐7) is overexpressed in various malignancies, few studies have
evaluated its role in epithelial ovarian cancer (EOC) invasion and metastasis. We report that …

Resveratrol suppresses tumor necrosis factor-α-induced fractalkine expression in endothelial cells

…, S Lee, KP Kang, DH Kim, SY Lee, JN So… - Molecular …, 2006 - ASPET
Up-regulation of fractalkine is involved in vascular and tissue damage in inflammatory
conditions. Resveratrol has been shown to have anti-inflammatory, antioxidant, and antitumor …

Global analysis of electroweak data in SO(10) SUSY GUTs

T Blažek, M Carena, S Raby, CEM Wagner - Physical Review D, 1997 - APS
We present the details of a global χ 2 analysis of electroweak data, including fermion masses
and mixing angles, in SO (10) SUSY GUTs. Just as precision electroweak data are used to …

Yeast two-hybrid: so many interactions,(in) so little time…

KH Young - Biology of reproduction, 1998 - academic.oup.com
Protein-protein interactions are essential to cellular mechanisms at all levels in biologically
responsive systems. These interactions occur extracellularly and include ligand-receptor …
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