Activation of calmodulin by various metal cations as a function of ionic radius.
SH Chao, Y Suzuki, JR Zysk, WY Cheung - Molecular pharmacology, 1984 - ASPET
The active form of calmodulin is a Ca2+ . calmodulin complex. The purpose of this investigation
was to determine whether other metal cations substitute for Ca2+ to activate calmodulin. …
was to determine whether other metal cations substitute for Ca2+ to activate calmodulin. …
Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone.
BD Gaylinn, JK Harrison, JR Zysk… - Molecular …, 1993 - academic.oup.com
GH-releasing hormone (GHRH), acting through the GHRH receptor (GHRH-R), plays a
pivotal role in the regulation of GH synthesis and secretion in the pituitary. It is possible that …
pivotal role in the regulation of GH synthesis and secretion in the pituitary. It is possible that …
Temporary sterility produced in male mice by 5-thio-D-glucose
JR Zysk, AA Bushway, RL Whistler… - Reproduction, 1975 - rep.bioscientifica.com
When 5-thio- d -glucose was fed to male mice at daily dose levels greater than 30 mg/kg
sperm development was completely inhibited within 3 weeks and remained so without …
sperm development was completely inhibited within 3 weeks and remained so without …
Stimulation of calmodulin by cadmium ion
Y Suzuki, SH Chao, JR Zysk, WY Cheung - Archives of toxicology, 1985 - Springer
Cd 2+ , a serious environmental pollutant in certain industrial regions, accumulates in mammalian
tissues with a very slow turnover. Using various criteria, we studied the ability of Cd 2+ …
tissues with a very slow turnover. Using various criteria, we studied the ability of Cd 2+ …
Calcium/calmodulin-dependent phosphorylation of vimentin in rat sertoli cells.
WA Spruill, JR Zysk, LL Tres… - Proceedings of the …, 1983 - National Acad Sciences
Ca2+-dependent protein phosphorylation and the role of calmodulin in this process was
investigated in subcellular fractions of primary cultures of rat Sertoli cells. Significant Ca2+/…
investigated in subcellular fractions of primary cultures of rat Sertoli cells. Significant Ca2+/…
A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats
…, R Houghten, CM Eppler, LA Price, JR Zysk - Molecular …, 1998 - ASPET
Somatostatin (SRIF) is the main inhibitory peptide regulating growth hormone (GH) secretion.
It has been difficult to establish the role of endogenous SRIF release in the absence of …
It has been difficult to establish the role of endogenous SRIF release in the absence of …
Parkin suppresses wild-type α-synuclein-induced toxicity in SHSY-5Y cells
…, CW Scott, JL Arriza, JD Reid, JR Zysk - Biochemical and …, 2003 - Elsevier
Current hypotheses concerning the mechanism of neuronal cell death in Parkinson’s disease
(PD) and related synucleopathies propose a functional interaction between parkin and α-…
(PD) and related synucleopathies propose a functional interaction between parkin and α-…
[HTML][HTML] Homogeneous pharmacologic and cell-based screens provide diverse strategies in drug discovery: somatostatin antagonists as a case study
JR Zysk, WR Baumbach - COMBINATORIAL CHEMISTRY AND …, 1998 - books.google.com
The development of high throughput, homogeneous pharmacologic and functional assays
and their implementation in screening combinatorial libraries has increased the pace of …
and their implementation in screening combinatorial libraries has increased the pace of …
Selective uptake of estrogenic compounds by Saccharomyces cerevisiae: a mechanism for antiestrogen resistance in yeast expressing the mammalian estrogen …
JR Zysk, B Johnson, BA Ozenberger, B Bingham… - …, 1995 - academic.oup.com
Estrogen antagonists such as ICI164,384 do not inhibit 17 beta-estradiol (E2)-dependent gene
activity in yeast expressing the mammalian estrogen receptor although these compounds …
activity in yeast expressing the mammalian estrogen receptor although these compounds …
Purification of a pituitary receptor for somatostatin. The utility of biotinylated somatostatin analogs.
CM Eppler, JR Zysk, M Corbett, HM Shieh - Journal of Biological Chemistry, 1992 - ASBMB
A somatostatin (SRIF) receptor and its associated Gi regulatory proteins was purified from
GH4C1 rat pituitary cells by: 1) saturation of the membrane-bound receptor with biotinyl-NH-[…
GH4C1 rat pituitary cells by: 1) saturation of the membrane-bound receptor with biotinyl-NH-[…