… A recent Cochrane Overview, found that the 0 to 30‐day mortality of patients undergoing high
or moderate cardiac risk procedures is lower in patients having an operation under neuraxial …

… of stress response markers, such as epinephrine, norepinephrine, cortisol and glucose, are
lower in patients for whom epidural analgesia is added to general anaesthesia (Guay 2006a)…

Background Various nerve blocks with local anaesthetic agents have been used to reduce
pain after hip fracture and subsequent surgery. This review was published originally in 1999 …

We have studied the contribution of the individual kinases of the MAP (mitogen-activated
protein) kinase family, including ERK (extracellular-signal regulated kinase), JNK/SAPK (c-JUN …

We report here the preclinical profile of etoricoxib (MK-0663) [5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)
pyridine], a novel orally active agent that selectively inhibits …

… J. Xu, RN Young, and R. Zamboni … J.; Young, RN; Zamboni, R.; Boyce, S.; Rupniak, N.;
Patrick, D.; Riendeau, DJ Pharmacol. Exp. Ther. … Chan, C.; Boyce, S.; Brideau, C.; Ford-Hutchinson …

The discoveries that cyclooxygenase (COX)-2 is an inducible form of COX involved in
inflammation and that COX-1 is the major isoform responsible for the production of prostaglandins (…

… Panels are available from Jean-Pierre Guay upon request. … These curves are available
from Jean-Pierre Guay on request. … be addressed to Jean-Pierre Guay, School of Criminology, …

DFU (5,5‐dimethyl‐3‐(3‐fluorophenyl)‐4‐(4‐methylsulphonyl)phenyl‐2(5H)‐furanone) was
identified as a novel orally active and highly selective cyclo‐oxygenase‐2 (COX‐2) inhibitor. …

A strain‐specific vaccine represents the best possible response to the threat of an influenza
pandemic. Rapid delivery of such a vaccine to the world's population before the peak of the …