User profiles for James Kean
James D. KeanOrygen Verified email at unimelb.edu.au Cited by 590 |
Structure of class B GPCR corticotropin-releasing factor receptor 1
K Hollenstein, J Kean, A Bortolato, RKY Cheng… - Nature, 2013 - nature.com
Structural analysis of class B G-protein-coupled receptors (GPCRs), cell-surface proteins
that respond to peptide hormones, has been restricted to the amino-terminal extracellular …
that respond to peptide hormones, has been restricted to the amino-terminal extracellular …
The development of preschool children of heroin-addicted mothers: a controlled study
GS Wilson, R McCreary, J Kean, JC Baxter - Pediatrics, 1979 - publications.aap.org
Disturbances of growth and behavior in infants and toddlers of women addicted to heroin
during pregnancy have been reported in uncontrolled studies. In this study, 3to 6-year-old …
during pregnancy have been reported in uncontrolled studies. In this study, 3to 6-year-old …
Intracellular allosteric antagonism of the CCR9 receptor
C Oswald, M Rappas, J Kean, AS Doré, JC Errey… - Nature, 2016 - nature.com
Chemokines and their G-protein-coupled receptors play a diverse role in immune defence by
controlling the migration, activation and survival of immune cells 1 . They are also involved …
controlling the migration, activation and survival of immune cells 1 . They are also involved …
Crystal structure of the GLP-1 receptor bound to a peptide agonist
A Jazayeri, M Rappas, AJH Brown, J Kean, JC Errey… - Nature, 2017 - nature.com
Glucagon-like peptide 1 (GLP-1) regulates glucose homeostasis through the control of insulin
release from the pancreas. GLP-1 peptide agonists are efficacious drugs for the treatment …
release from the pancreas. GLP-1 peptide agonists are efficacious drugs for the treatment …
The Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review of Randomized, Controlled Human Clinical Trials
Objectives: Traditional knowledge suggests that Bacopa monnieri enhances cognitive
performance. Such traditional beliefs have now been scientifically tested through a handful of …
performance. Such traditional beliefs have now been scientifically tested through a handful of …
Complementary medicines (herbal and nutritional products) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD): a systematic review of the evidence
OVERVIEW: Complementary and Alternative Medicines (CAMs) are frequently given to
children and adolescents for reputed benefits in the treatment of hyperkinetic and concentration …
children and adolescents for reputed benefits in the treatment of hyperkinetic and concentration …
An Acute, Double‐Blind, Placebo‐Controlled Crossover Study of 320 mg and 640 mg Doses of a Special Extract of Bacopa monnieri (CDRI 08) on Sustained …
Standardized extracts of the traditional Ayurvedic medicine Bacopa monnieri (BM) (Brahmi)
have been recently shown to have cognitive enhancing effects in chronic administration …
have been recently shown to have cognitive enhancing effects in chronic administration …
[HTML][HTML] Digital technology for addressing cognitive impairment in recent-onset psychosis: a perspective
Cognitive impairments in psychosis negatively impact functional recovery and quality of life.
Existing interventions for improving cognitive impairment in recent-onset psychosis show …
Existing interventions for improving cognitive impairment in recent-onset psychosis show …
A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations
Objectives Clinicians utilise critical research to advance their knowledge when prescribing
standard and alternative therapies for developmental disorders. Recent research has …
standard and alternative therapies for developmental disorders. Recent research has …
A molecular pharmacologist's guide to G protein–coupled receptor crystallography
CL Piscitelli, J Kean, C de Graaf, X Deupi - Molecular pharmacology, 2015 - ASPET
G protein–coupled receptor (GPCR) structural biology has progressed dramatically in the
last decade. There are now over 120 GPCR crystal structures deposited in the Protein Data …
last decade. There are now over 120 GPCR crystal structures deposited in the Protein Data …