[HTML][HTML] Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
Background G protein coupled receptors (GPCRs) are one of the most widely studied gene
superfamilies. Thousands of GPCR research studies have utilized heterologous expression …
superfamilies. Thousands of GPCR research studies have utilized heterologous expression …
Cloning and molecular characterization of the rat CB2 cannabinoid receptor
SM Brown, J Wager-Miller, K Mackie - Biochimica et Biophysica Acta (BBA) …, 2002 - Elsevier
The rat peripheral cannabinoid receptor (rCB2) was cloned from a Sprague–Dawley rat
spleen cDNA library and when translated, encodes a protein of 410 amino acids. Alignment of …
spleen cDNA library and when translated, encodes a protein of 410 amino acids. Alignment of …
Functional selectivity in CB2 cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB2 ligands
BK Atwood, J Wager-Miller, C Haskins, A Straiker… - Molecular …, 2012 - ASPET
Receptor internalization increases the flexibility and scope of G protein-coupled receptor (GPCR)
signaling. CB 1 and CB 2 cannabinoid receptors undergo internalization after …
signaling. CB 1 and CB 2 cannabinoid receptors undergo internalization after …
Dimerization of G protein-coupled receptors: CB1 cannabinoid receptors as an example
J Wager-Miller, R Westenbroek, K Mackie - Chemistry and physics of lipids, 2002 - Elsevier
A polyclonal antibody directed towards the last 73 amino acid residues of the rat type 1
cannabinoid (CB1) receptor strongly and exclusively labels a high molecular weight (between …
cannabinoid (CB1) receptor strongly and exclusively labels a high molecular weight (between …
[HTML][HTML] GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination
The G-protein coupled receptor 55 (GPR55) is activated by lysophosphatidylinositols and
some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/…
some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/…
Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections
CS Wu, J Zhu, J Wager‐Miller, S Wang… - European Journal of …, 2010 - Wiley Online Library
A role for endocannabinoid signaling in neuronal morphogenesis as the brain develops has
recently been suggested. Here we used the developing somatosensory circuit as a model …
recently been suggested. Here we used the developing somatosensory circuit as a model …
Chronic Adolescent Δ9-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by …
…, J Winstone, E Leishman, J Wager-Miller… - Cannabis and …, 2017 - liebertpub.com
Introduction: The high prevalence of adolescent cannabis use, the association between this
use and later psychiatric disease, and increased access to high-potency cannabis highlight …
use and later psychiatric disease, and increased access to high-potency cannabis highlight …
Sex-dependent effects of in utero cannabinoid exposure on cortical function
…, M Serviado, O Lassalle, M Murphy, J Wager-Miller… - Elife, 2018 - elifesciences.org
10.7554/eLife.36234.001 Cannabinoids can cross the placenta, thus may interfere with fetal
endocannabinoid signaling during neurodevelopment, causing long-lasting deficits. Despite …
endocannabinoid signaling during neurodevelopment, causing long-lasting deficits. Despite …
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons
Depolarization-induced suppression of excitation (DSE) is a major form of cannabinoid-mediated
short-term retrograde neuronal plasticity and is found in numerous brain regions. …
short-term retrograde neuronal plasticity and is found in numerous brain regions. …
Architecture of cannabinoid signaling in mouse retina
…, J Radicke, BF Cravatt, J Wager‐Miller… - Journal of …, 2010 - Wiley Online Library
Cannabinoid receptors and their ligands constitute an endogenous signaling system that is
found throughout the body, including the eye. This system can be activated by Δ 9 ‐…
found throughout the body, including the eye. This system can be activated by Δ 9 ‐…