Administration of ammonium salts of perfluorooctanoate (PFOA) to rats results in peroxisome
proliferation and benign liver tumors, events associated with activation of the nuclear …

Administration of phthalates is known to cause toxicity and liver cancer in rodents through
the activation of peroxisome proliferator-activated receptors (PPARs), and the monoesters …

Selenium is an essential micronutrient that suppresses the redox-sensitive transcription
factor NF-κB-dependent pro-inflammatory gene expression. To understand the molecular …

2-Arachidonyl glycerol (2-AG) is an endogenous arachidonic acid derivative that binds
cannabinoid receptors CB1 and CB2 and is hence termed an endocannabinoid. 2-AG also …

The inducible isoform of nitric oxide synthase (iNOS) is implicated in atherosclerosis,
malignancy, rheumatoid arthritis, tissue and reperfusion injuries. A key determinant of the pro-…

Selenium (Se) is an essential micronutrient for all mammalian species and is associated with
a variety of physiological functions, notably immune system, in the form of selenoproteins. …

Liver insufficiency and damage are major causes of death and disease worldwide and may
result from exposure to environmental toxicants, specific combinations or dosages of …

myo-Inositol oxygenase (MIOX) catalyses the first committed step in the only pathway of myo-inositol
catabolism, which occurs predominantly in the kidney. The enzyme is a non-haem-…

Targeting cancer stem cells is of paramount importance in successfully preventing cancer
relapse. Recently, in silico screening of public gene-expression datasets identified …

Omega-3-PUFAs, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are
associated with prevention of various aspects of metabolic syndrome. In the present studies, the …