User profiles for Jiayin Diao
 | Jiayin DiaoPhD candidate, Monash University Verified email at monash.edu Cited by 92 |
Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus‐induced lung inflammation in mice
Background and objective Influenza A viruses (IAV) cause respiratory tract infections that
can be fatal when the virus spreads to the alveolar space (ie alveolitis), and this is mainly …
can be fatal when the virus spreads to the alveolar space (ie alveolitis), and this is mainly …
Therapeutic opportunities of targeting allosteric binding sites on the calcium-sensing receptor
The CaSR is a class CG protein-coupled receptor (GPCR) that acts as a multimodal chemosensor
to maintain diverse homeostatic functions. The CaSR is a clinical therapeutic target in …
to maintain diverse homeostatic functions. The CaSR is a clinical therapeutic target in …
Application of a sulfoxonium ylide electrophile to generate cathepsin X-selective activity-based probes
Cathepsin X/Z/P is cysteine cathepsin with unique carboxypeptidase activity. Its expression
is associated with cancer and neurodegenerative diseases, although its roles during normal …
is associated with cancer and neurodegenerative diseases, although its roles during normal …
Identification of global and ligand-specific calcium sensing receptor activation mechanisms
Calcium sensing receptor (CaSR) positive allosteric modulators (PAMs) are therapeutically
important. However, few are approved for clinical use, in part due to complexities in …
important. However, few are approved for clinical use, in part due to complexities in …
Evaluation of operational models of agonism and allosterism at receptors with multiple orthosteric binding sites
Current operational models of agonism and allosterism quantify ligand actions at receptors
where agonist concentration-response relationships are nonhyperbolic by introduction of a …
where agonist concentration-response relationships are nonhyperbolic by introduction of a …
An integrated strategy to qualitatively differentiate components of raw and processed Viticis Fructus based on NIR, HPLC and UPLC-MS Analysis
J Diao, C Xu, H Zheng, S He, S Wang - Planta Medica, 2018 - thieme-connect.com
Viticis Fructus is a traditional Chinese herbal drug processed by various methods to achieve
different clinical purposes. Thermal treatment potentially alters chemical composition, which …
different clinical purposes. Thermal treatment potentially alters chemical composition, which …
Calcium-Sensing Receptor Negative Allosteric Modulators Oppose Contraction of Mouse Airways
Asthma is a heterogeneous chronic airway disease with an unmet need for improved
therapeutics in uncontrolled severe disease. The calcium-sensing receptor (CaSR) is a G protein–…
therapeutics in uncontrolled severe disease. The calcium-sensing receptor (CaSR) is a G protein–…
[HTML][HTML] Direct syntheses of stereoisomers of 3-fluoro GABA and β-fluoroamine analogues of the calcium receptor (CaR) agonists, cinacalcet, tecalcet, fendiline and …
Synthetic routes following a sequential MacMillan organocatalytic asymmetric α-fluorination
protocol for aldehydes and then reductive amination, have allowed ready access to …
protocol for aldehydes and then reductive amination, have allowed ready access to …
The calcium-sensing receptor CaSR mediates airway contraction in a house dust mite model of allergic airway disease
Introduction: The CaSR detects changes in extracellular calcium to maintain homeostasis (Leach,
Trends Pharmacol Sci, 2015). This putative drug target is upregulated in asthma, and …
Trends Pharmacol Sci, 2015). This putative drug target is upregulated in asthma, and …
An integrated strategy to qualitatively differentiate components of raw and processed Viticis Fructus based on NIR, HPLC and UPLC-MS analysis.
DJY Diao JiaYin, XC Xu Can, ZHT Zheng HuiTing… - 2018 - cabidigitallibrary.org
Viticis Fructus is a traditional Chinese herbal drug processed by various methods to achieve
different clinical purposes. Thermal treatment potentially alters chemical composition, which …
different clinical purposes. Thermal treatment potentially alters chemical composition, which …