The epidermal growth factor receptor (EGFR) has been one of the most intensely studied
cell surface receptors due to its well-established roles in developmental biology, tissue …

A properly functioning cornea is critical to clear vision and healthy eyes. As the most anterior
portion of the eye, it plays an essential role in refracting light onto the retina and as an …

Purpose.: To provide a comprehensive study of the biological role and therapeutic potential
of six endogenous epidermal growth factor receptor (EGFR) ligands in corneal epithelial …

There are 13 known endogenous ligands for the epidermal growth factor receptor (EGFR) and
its closely related ErbB receptor family members. We previously reported that betacellulin (…

A substantial fraction of individuals vaccinated against anthrax have low to immeasurable
levels of serum Lethal Toxin (LeTx)-neutralizing activity. The only known correlate of protection …

Purpose:: Experimentally it has been shown that epidermal growth factor (EGF) and its receptor
(EGFR/ErbB1) are necessary and sufficient for promoting the cellular events associated …

All criminalistics laboratories in the United States were surveyed and asked to provide
information about their service characteristics, personnel, evidence caseloads, involvement in …

The epidermal growth factor receptor (EGFR) has been shown to be necessary and sufficient
for mediating corneal epithelial homeostasis and wound healing. Experimentally, activation …

Cells within a tumor are highly heterogeneous with respect to a wide range of genotypic and
phenotypic characteristics. The latter include such properties as growth, survival, invasion, …

Among novel promising approaches that have recently entered the scene of anti-cancer
therapy angiogenesis inhibition and targeting cancer-causing genes (eg oncogenes) are of …